1. Gene
  2. EMC9 - ER membrane protein complex subunit 9 Gene

EMC9 - ER membrane protein complex subunit 9 Gene

中文名称:ER 膜蛋白复合亚基 9

种属: Homo sapiens

同用名: CGI-112; FAM158A; C14orf122

基因 ID: 51016 | 基因类型: protein coding

关于 EMC9

This gene has 7 transcripts (splice variants), 1 gene allele, 187 orthologues and 1 paralogue. Ubiquitous expression in appendix (RPKM 5.4), duodenum (RPKM 4.9) and 25 other tissues.

功能概要

有助于膜插入酶活性。通过停止转移膜锚序列和尾部锚定膜蛋白插入 ER 膜参与蛋白质插入 ER 膜。位于细胞质中。 EMC 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in cytoplasm. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC9 基因产物(5)

mRNA Protein Name
NM_001346874.2 NP_001333803.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346875.2 NP_001333804.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346876.2 NP_001333805.1 ER membrane protein complex subunit 9 isoform b precursor
NM_001346877.2 NP_001333806.1 ER membrane protein complex subunit 9 isoform b precursor
NM_016049.4 NP_057133.2 ER membrane protein complex subunit 9 isoform a

EMC9 蛋白结构

UPF0172

UPF0172: Uncharacterised protein family (UPF0172) (1 - 192)

  • 0
  • 100
  • 208 a.a.
蛋白主名 其他名称

ER membrane protein complex subunit 9

UPF0172 protein FAM158A

EMC9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
35271311
种属内
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
33961781
种属内
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Anti Tag CoIP
28514442
种属内
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Y2H Array
25416956
种属内
EMC9 Q9Y3B6 EMC2 Homo sapiens Q15006
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Intraocular Retinoblastoma

Pediatric Intraocular Retinoblastoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus EMC9 MGD MGI:1934682
Felis catus EMC9 VGNC VGNC:61838
Bos taurus EMC9 VGNC VGNC:28468
Macaca mulatta EMC9 VGNC VGNC:72077
Canis familiaris EMC9 VGNC VGNC:40338
Rattus norvegicus EMC9 RGD RGD:1308113