2. Gene
  3. COPZ2 - COPI coat complex subunit zeta 2 Gene

COPZ2 - COPI coat complex subunit zeta 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：COPI 外套复杂亚基 zeta 2

种属: Homo sapiens

同用名: zeta2-COP

基因 ID: 51226 | 基因类型: protein coding

关于 COPZ2

Cytogenetic location: 17q21.32 Genomic coordinates (GRCh38): 17:48,026,167-48,048,053 (from NCBI)

This gene has 10 transcripts (splice variants), 192 orthologues and 1 paralogue. Broad expression in fat (RPKM 13.1), prostate (RPKM 4.4) and 22 other tissues.

功能概要

该基因编码衔接复合物小亚基家族的成员。编码的蛋白质是 coatomer 蛋白复合物的一个亚基，coatomer 蛋白复合物是一种七亚基复合物，在 COPI 型、非网格蛋白包被的囊泡的形成中起作用。 COPI 囊泡在二赖氨酸标记蛋白的逆行高尔基体到 ER 转运中发挥作用。[RefSeq 提供，2014 年 2 月]

This gene encodes a member of the adaptor complexes small subunit family. The encoded protein is a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. [provided by RefSeq, Feb 2014]

COPZ2 基因产物(1)

mRNA Protein Name
NM_016429.4 NP_057513.1 coatomer subunit zeta-2
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of COPI vesicle coat IDA
IDA: 通过直接分析推断
14729954 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

COPZ2 蛋白结构

Clat_adaptor_s

Clat_adaptor_s: Clathrin adaptor complex small chain (43 - 180)

  • 0
  • 100
  • 208 a.a.
蛋白主名 其他名称

coatomer subunit zeta-2

coatomer protein complex subunit zeta 2

关联疾病

疾病名称 别名
Penis Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Penis

Epidermoid Cell Carcinoma Of Penis

Squamous Cell Carcinoma Of The Penis

Penile Squamous Cell Carcinoma
Intellectual Developmental Disorder, Autosomal Dominant 56

Mental Retardation, Autosomal Dominant 56

MRD56

Autosomal Dominant Mental Retardation 56

Autosomal Dominant Intellectual Developmental Disorder 56

Autosomal Dominant Intellectual Developmental Disorder-56
Developmental And Epileptic Encephalopathy 48

DEE48

Epileptic Encephalopathy, Early Infantile, 48

Eiee48

Developmental And Epileptic Encephalopathy, 48

Early Infantile Epileptic Encephalopathy 48
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03035 COPZ2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus COPZ2 VGNC VGNC:98889
Canis familiaris COPZ2 VGNC VGNC:39515
Rattus norvegicus COPZ2 RGD RGD:1306948
Macaca mulatta COPZ2 VGNC VGNC:71220
Bos taurus COPZ2 VGNC VGNC:27608
Mus musculus COPZ2 MGD MGI:1929008
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