2. Gene
  3. PDZD11 - PDZ domain containing 11 Gene

PDZD11 - PDZ domain containing 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 PDZ 结构域 11

种属: Homo sapiens

同用名: PISP; AIPP1; PDZK11

基因 ID: 51248 | 基因类型: protein coding

关于 PDZD11

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:70,286,595-70,289,927 (from NCBI)

This gene has 6 transcripts (splice variants), 215 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 12.6), thyroid (RPKM 10.9) and 25 other tissues.

功能概要

启用蛋白质 C 末端结合活性。参与孔复合体组装。位于基底外侧质膜和细胞质中。孔复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein C-terminus binding activity. Involved in pore complex assembly. Located in basolateral plasma membrane and cytosol. Part of pore complex. [provided by Alliance of Genome Resources, Apr 2022]

PDZD11 基因产物(6)

mRNA Protein Name
NM_001370174.1 NP_001357103.1 PDZ domain-containing protein 11 isoform 1
NM_001370175.1 NP_001357104.1 PDZ domain-containing protein 11 isoform 1
NM_001370176.1 NP_001357105.1 PDZ domain-containing protein 11 isoform 1
NM_001370177.1 NP_001357106.1 PDZ domain-containing protein 11 isoform 1
NM_001370178.1 NP_001357107.1 PDZ domain-containing protein 11 isoform 2
NM_016484.5 NP_057568.1 PDZ domain-containing protein 11 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12763866 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in pore complex assembly IMP
IMP: 通过突变表型推断
30463011 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
12763866 GOA
located in cytosol IDA
IDA: 通过直接分析推断
12763866 GOA
part of pore complex IMP
IMP: 通过突变表型推断
30463011 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PDZD11 蛋白结构

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (48 - 124)

  • 0
  • 100
  • 140 a.a.
蛋白主名 其他名称

PDZ domain-containing protein 11

ATPase-interacting PDZ protein

PDZD11 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PDZD11 Q5EBL8 MAGI2 Homo sapiens Q86UL8-2
Y2H Prey Pooling
32296183
种属内
PDZD11 Q5EBL8 MAGI2 Homo sapiens Q86UL8-2
Validated Y2H
32296183
种属内
PDZD11 Q5EBL8 MAGI2 Homo sapiens Q86UL8-2
Y2H Array
32296183
种属内
PDZD11 Q5EBL8 SLC5A6 Homo sapiens Q9Y289
Pull Down
21183659
种属内
PDZD11 Q5EBL8 SLC5A6 Homo sapiens Q9Y289
Y2H
21183659
种属内
PDZD11 Q5EBL8 SLC5A6 Homo sapiens Q9Y289
Confocal
21183659
种属内
PDZD11 Q5EBL8 SLC5A6 Homo sapiens Q9Y289
Anti Tag CoIP
21183659
种属内
PDZD11 Q5EBL8 ATP7A Homo sapiens Q04656
Anti Tag CoIP
16051599
种属内
PDZD11 Q5EBL8 ATP7A Homo sapiens Q04656
Y2H Pooling
16051599
种属内
PDZD11 Q5EBL8 ATP7A Homo sapiens Q04656
Y2H Array
16051599
种属内
PDZD11 Q5EBL8 ATP7A Homo sapiens Q04656
Y2H
16051599
种属内
PDZD11 Q5EBL8 PLEKHA5 Homo sapiens Q9HAU0
Y2H Array
32296183
种属内
PDZD11 Q5EBL8 PLEKHA5 Homo sapiens Q9HAU0
Validated Y2H
32296183
种属内
PDZD11 Q5EBL8 PLEKHA5 Homo sapiens Q9HAU0
Y2H Prey Pooling
32296183
种属内
PDZD11 Q5EBL8 PLEKHA5 Homo sapiens Q9HAU0
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 PDZD11 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77130 PDZD11 Protein, Human (His) Q5EBL8-1 (D2-H140) ≥95%

关联疾病

疾病名称 别名
Purulent Acute Otitis Media

Acute Suppurative Otitis Media

Acute Or Subacute Suppurative Otitis Media

Acute Or Subacute Purulent Otitis Media
Epiphyseal Dysplasia, Multiple, 2

EDM2

Multiple Epiphyseal Dysplasia 2

Dysplasia, Epiphyseal, Multiple, Type 2
Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly
Epiphyseal Dysplasia, Multiple, 3

EDM3

Multiple Epiphyseal Dysplasia 3

Epiphyseal Dysplasia, Multiple, 3, With Or Without Myopathy

Multiple Epiphyseal Dysplasia 3 With Or Without Myopathy

Epiphyseal Dysplasia Multiple 3

Dysplasia, Epiphyseal, Multiple, Type 3
Multiple Epiphyseal Dysplasia

Med

Polyepiphyseal Dysplasia

Edm

Epiphyseal Dysplasia, Multiple, 1

Epiphyseal Dysplasia, Multiple, 2

Epiphyseal Dysplasia, Multiple, 3

Epiphyseal Dysplasia, Multiple, 4

Epiphyseal Dysplasia, Multiple, 5

Epiphyseal Dysplasia, Multiple

Edm1

Edm2

Edm3

Edm4

Edm5

Epiphyseal Dysplasia, Fairbank Type

Epiphyseal Dysplasia, Ribbing Type

Multiple Epiphyseal Dysplasia, Autosomal Dominant

Multiple Epiphyseal Dysplasia, Autosomal Recessive

Rmed

Dysplasia, Epiphyseal, Multiple

Osteochondrodysplasias
Suppurative Otitis Media

Otitis Media With Effusion - Purulent

Purulent Otitis Media

Otitis Media, Suppurative
Osteochondrodysplasia

Skeletal Dysplasia

Chondrodystrophy

Congenital Anomaly Of Cartilage

Osteochondrodysplasias

Cartilage Development Disorder

Osteochondrodysplasia Syndrome

Dysplasia, Skeletal

Mucopolysaccharidosis Iv
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10300 PDZD11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PDZD11 VGNC VGNC:32724
Mus musculus PDZD11 MGD MGI:1919871
Rattus norvegicus PDZD11 RGD RGD:1560007
Canis familiaris PDZD11 VGNC VGNC:44399
Others PDZD11 NCBI
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