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  2. SLC15A3 - solute carrier family 15 member 3 Gene

SLC15A3 - solute carrier family 15 member 3 Gene

中文名称:溶质载体家族 15 成员 3

种属: Homo sapiens

同用名: OCTP; PHT2; PTR3

基因 ID: 51296 | 基因类型: protein coding

关于 SLC15A3

Cytogenetic location: 11q12.2 Genomic coordinates (GRCh38): 11:60,937,084-60,952,176 (from NCBI)

This gene has 14 transcripts (splice variants), 121 orthologues and 4 paralogues. Broad expression in spleen (RPKM 20.2), lung (RPKM 17.9) and 23 other tissues.

功能概要

启用二肽跨膜转运蛋白活性。参与跨质膜的二肽输入。位于细胞内膜界的细胞器中。 [由基因组资源联盟提供,2022 年 4 月]

Enables dipeptide transmembrane transporter activity. Involved in dipeptide import across plasma membrane. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

SLC15A3 基因产物(1)

mRNA Protein Name
NM_016582.3 NP_057666.1 solute carrier family 15 member 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dipeptide transmembrane transporter activity IDA
IDA: 通过直接分析推断
31073693 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
24695226 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in dipeptide import across plasma membrane IDA
IDA: 通过直接分析推断
31073693 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SLC15A3 蛋白结构

PTR2

PTR2: POT family (101 - 500)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 581 a.a.
蛋白主名 其他名称

solute carrier family 15 member 3

osteoclast transporter

SLC15A3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SLC15A3 Q8IY34 KRTAP12-2 Homo sapiens P59991
MAPPIT
32296183
种属内
SLC15A3 Q8IY34 KRTAP12-2 Homo sapiens P59991
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 KRTAP9-8 Homo sapiens Q9BYQ0
Validated Y2H
32296183
种属内
SLC15A3 Q8IY34 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Array
32296183
种属内
SLC15A3 Q8IY34 KRTAP9-8 Homo sapiens Q9BYQ0
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 KRTAP19-2 Homo sapiens Q3LHN2
Y2H Array
32296183
种属内
SLC15A3 Q8IY34 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 KRTAP5-9 Homo sapiens P26371
Y2H Array
32296183
种属内
SLC15A3 Q8IY34 SLC15A4 Homo sapiens Q8N697
Anti Tag CoIP
24695226
种属内
SLC15A3 Q8IY34 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 MDFI Homo sapiens Q99750
Validated Y2H
32296183
种属内
SLC15A3 Q8IY34 MDFI Homo sapiens Q99750
Y2H Array
32296183
种属内
SLC15A3 Q8IY34 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
种属内
SLC15A3 Q8IY34 HOXA1 Homo sapiens P49639
Y2H Array
32296183
种属内
SLC15A3 Q8IY34 NOD2 Homo sapiens Q9HC29
Anti Tag CoIP
24695226
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Hypotrichosis 4

HYPT4

Marie Unna Hereditary Hypotrichosis 1

Muhh1

Hypotrichosis, Marie Unna Type, 1

Hypotrichosis Marie Unna 1

Marie Unna Hereditary Hypotrichosis Type 1

Hypotrichosis, Hereditary, Marie Unna Type, 1

Hypotrichosis, Type 4

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SLC15A3 RGD RGD:628663
Macaca mulatta SLC15A3 VGNC VGNC:77504
Canis familiaris SLC15A3 VGNC VGNC:52046
Bos taurus SLC15A3 VGNC VGNC:34680
Felis catus SLC15A3 VGNC VGNC:65202
Mus musculus SLC15A3 MGD MGI:1929691