PDC - phosducin Gene

中文名称：磷导素

种属: Homo sapiens

同用名: PHD; MEKA; PhLP; PhLOP

基因 ID: 5132 | 基因类型: protein coding

关于 PDC

Cytogenetic location: 1q31.1 Genomic coordinates (GRCh38): 1:186,443,566-186,461,114 (from NCBI)

This gene has 2 transcripts (splice variants), 269 orthologues and 4 paralogues. Low expression observed in reference dataset.

功能概要

该基因编码一种磷蛋白，位于视网膜视杆细胞的外节和内节。这种蛋白质可能参与视觉光转导的调节或光感受器代谢的整合。它通过与视网膜 G 蛋白转导蛋白的 β 和 γ 亚基相互作用来调节光转导级联。该基因是色素性视网膜炎和 II 型 Usher 综合征的潜在候选基因。已经鉴定出编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

PDC 基因产物(2)

mRNA	Protein	Name
NM_002597.5	NP_002588.3	phosducin isoform a
NM_022576.4	NP_072098.1	phosducin isoform b

PDC 蛋白结构

Phosducin

0
100
200
246 a.a.

蛋白主名

其他名称

phosducin

33 kDa phototransducing protein

关联疾病

疾病名称

别名

Pollen Allergy

Hay Fever

Tomato Allergy

Solanum Lycopersicum Fruit Allergy

Timothy Grass Allergy

Melon Allergy

Cucumis Melo Fruit Allergy

Orange Allergy

Citrus Sinensis Fruit Allergy

Apple Allergy

Malus Domestica Fruit Allergy

Thunderstorm Triggered Asthma

Thunderstorm Asthma

Thunderstorm Related Asthma

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Peach Allergy

Prunus Persica Fruit Allergy

Fish Allergy

Allergy To Fish

Splenic Flexure Cancer

Ca Splenic Flexure - Colon	Malignant Neoplasm Of Splenic Flexure
Malignant Tumor Of Splenic Flexure	Malignant Neoplasm Of Splenic Flexure Of Colon

Usher Syndrome

Deafness-Retinitis Pigmentosa Syndrome	Dystrophia Retinae Pigmentosa-Dysostosis Syndrome
Graefe-Usher Syndrome	Hallgren Syndrome
Usher'S Syndrome	Retinitis Pigmentosa-Deafness Syndrome
Retinitis Pigmentosa-Hearing Loss Syndrome	Ush
Usher Syndromes

Fruit Allergy

Allergy To Fruit

Legume Allergy

Fabaceae Allergy

Respiratory Allergy

Airway Allergy

Nasal Cavity Disease

Disorder Of Nasal Cavity

Nose Disease

Nose Diseases	Disorder Of The Nose
Nasal Disorder	Abnormality Of The Nose

Leber Plus Disease

Leber Congenital Amaurosis	Lca
Leber'S Amaurosis	Leber'S Disease
Amaurosis Congenita Of Leber	Amaurosis Congenita Of Leber, Type 1
Lhon Plus Disease	Congenital Absence Of The Rods And Cones
Congenital Retinal Blindness	Crb
Congenital Amaurosis Of Retinal Origin	Leber'S Congenital Amaurosis
Leber Congenital Amaurosis 1	Leber'S Congenital Tapetoretinal Degeneration
Leber'S Congenital Tapetoretinal Dysplasia	Lca1
Leber Congenital Amaurosis Type 1	Retinal Blindness, Congenital
Amaurosis, Leber Congenital	Dysgenesis Neuroepithelialis Retinae
Hereditary Epithelial Dysplasia Of Retina	Hereditary Retinal Aplasia
Heredoretinopathia Congenitalis	Leber Abiotrophy
Leber Congenital Tapetoretinal Degeneration	Lebers Congenital Amaurosis
Optic Atrophy, Hereditary, Leber

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

目录号	产品名	作用方式	纯度	是否罕见病
HY-P99536	Tagraxofusp	Inhibitor	/	否

目录号	产品名	作用方式	纯度	Phase
HY-148511	Vidutolimod	Agonist	/	Phase 3
HY-139567	Afimetoran		98.76%	Phase 2

目录号	产品名	作用方式	纯度	Phase
HY-P99226	Daxdilimab		96.58%	Phase 2

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-12836A	IFN alpha-IFNAR-IN-1 hydrochloride	Inhibitor	99.87%	否
HY-150741	ODN 2216		/	否
HY-132296	GSK215	Inhibitor	99.85%	否
HY-150741C	ODN 2216 sodium	Activator	97.88%	否
HY-148511A	Vidutolimod sodium	Inhibitor	90.20%	否
HY-P4160	PDC31	Inhibitor	99.76%	否
HY-12836	IFN alpha-IFNAR-IN-1	Inhibitor	/	否
HY-155393	PROTAC BRD4 Degrader-22		/	否
HY-160231	ssRNA42 sodium	Activator	/	否
HY-P1094	AZ-10417808	Inhibitor	/	否
HY-RS10184	PDC Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	PDC	VGNC	VGNC:106467
Canis familiaris	PDC	VGNC	VGNC:44333
Mus musculus	PDC	MGD	MGI:98090
Bos taurus	PDC	VGNC	VGNC:32656
Rattus norvegicus	PDC	RGD	RGD:3277
Macaca fascicularis	PDC	NCBI	NCBI:102141993
Others	PDC	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PDC - phosducin Gene

关于 PDC

功能概要

PDC 基因产物(2)

PDC 蛋白结构

关联疾病

直系同源

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PDC - phosducin Gene

关于 PDC

功能概要

PDC 基因产物(2)

PDC 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z