2. Gene
  3. EMCN - endomucin Gene

EMCN - endomucin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：内粘蛋白

种属: Homo sapiens

同用名: EMCN2; MUC14

基因 ID: 51705 | 基因类型: protein coding

关于 EMCN

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:100,395,341-100,518,022 (from NCBI)

This gene has 10 transcripts (splice variants) and 106 orthologues. Broad expression in kidney (RPKM 11.5), lung (RPKM 11.1) and 19 other tissues.

功能概要

EMCN 是一种粘蛋白样唾液酸糖蛋白，可干扰粘着斑复合物的组装并抑制细胞与细胞外基质之间的相互作用 (Kinoshita 等人，2001 [PubMed 11418125]) 。[OMIM 提供，2008 年 3 月]

EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix (Kinoshita et al., 2001 [PubMed 11418125]).[supplied by OMIM, Mar 2008]

EMCN 基因产物(2)

mRNA Protein Name
NM_001159694.2 NP_001153166.1 endomucin isoform 2 precursor
NM_016242.4 NP_057326.2 endomucin isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EMCN 蛋白结构

Endomucin

Endomucin: Endomucin (1 - 261)

  • 0
  • 100
  • 200
  • 261 a.a.
蛋白主名 其他名称

endomucin

MUC-14

关联疾病

疾病名称 别名
Nephrotic Syndrome, Type 10

NPHS10

Nephrotic Syndrome Type 10

Idiopathic Steroid-Sensitive Nephrotic Syndrome

Nephrotic Syndrome 10
Hypotrichosis-Lymphedema-Telangiectasia-Renal Defect Syndrome

Glomerulonephritis With Sparse Hair And Telangiectases

Telangiectatic Membranoproliferative Glomerulonephritis

HLTRS

Hypotrichosis-Lymphedema-Telangiectasia-Membranoproliferative Glomerulonephritis Syndrome

Hlt-Renal Defect Syndrome

Glomerulonephritis Sparse Hair Telangiectases
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04344 EMCN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus EMCN VGNC VGNC:53710
Canis familiaris EMCN VGNC VGNC:40339
Mus musculus EMCN MGD MGI:1891716
Macaca mulatta EMCN VGNC VGNC:100223
Rattus norvegicus EMCN RGD RGD:1303218
Felis catus EMCN VGNC VGNC:61839
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