2. Gene
  3. PHAX - phosphorylated adaptor for RNA export Gene

PHAX - phosphorylated adaptor for RNA export Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：用于 RNA 输出的磷酸化接头

种属: Homo sapiens

同用名: RNUXA

基因 ID: 51808 | 基因类型: protein coding

关于 PHAX

Cytogenetic location: 5q23.2 Genomic coordinates (GRCh38): 5:126,600,947-126,627,252 (from NCBI)

This gene has 5 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in brain (RPKM 11.7), endometrium (RPKM 7.4) and 25 other tissues.

功能概要

启用 mRNA 帽结合复合物结合活性。参与 RNA 稳定。位于中心体和核质中。核糖核蛋白复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables mRNA cap binding complex binding activity. Involved in RNA stabilization. Located in centrosome and nucleoplasm. Part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]

PHAX 基因产物(1)

mRNA Protein Name
NM_032177.4 NP_115553.2 phosphorylated adapter RNA export protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA cap binding complex binding IDA
IDA: 通过直接分析推断
28297668 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
26382858 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in RNA stabilization IMP
IMP: 通过突变表型推断
28297668 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
28297668 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PHAX 蛋白结构

RNA_GG_bind

RNA_GG_bind: PHAX RNA-binding domain (229 - 315)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
蛋白主名 其他名称

phosphorylated adapter RNA export protein

RNA U small nuclear RNA export adapter protein

关联疾病

疾病名称 别名
Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant

ADLD

Adult-Onset Autosomal Dominant Demyelinating Leukodystrophy

Leukodystrophy, Adult-Onset, Autosomal Dominant

Adult-Onset Autosomal Dominant Leukodystrophy

Autosomal Dominant Leukodystrophy With Autonomic Disease

Autosomal Dominant Adult-Onset Demyelinating Leukodystrophy

Multiple Sclerosis-Like Disorder

Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type, Formerly

Autosomal-Dominant Or Late-Onset Type Pelizaeus-Merzbacher Disease

Pelizaeus-Merzbacher Disease, Autosomal Dominant Or Late-Onset Type

Adult-Onset Autosomal Dominant Leukodystrophy With Autonomic Symptoms

Lmnb1-Related Adult-Onset Autosomal Dominant Leukodystrophy

Leukodystrophy, Demyelinating, Autosomal Dominant, Adult-Onset

Pelizaeus-Merzbacher Disease Autosomal Dominant

Pelizaeus-Merzbacher Disease Late-Onset Type

Adult Onset Autosomal Dominant Leukodystrophy
Retinitis Pigmentosa 57

RP57

Pde6g-Related Retinitis Pigmentosa

Retinitis Pigmentosa, Type 57
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70393D Human Factor Alpha XIIa / 否
HY-RS10406 PHAX Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PHAX MGD MGI:1891839
Macaca mulatta PHAX VGNC VGNC:97805
Felis catus PHAX VGNC VGNC:64131
Rattus norvegicus PHAX RGD RGD:708448
Bos taurus PHAX VGNC VGNC:32807
Canis familiaris PHAX VGNC VGNC:51915
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