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  2. TAS2R5 - taste 2 receptor member 5 Gene

TAS2R5 - taste 2 receptor member 5 Gene

中文名称:味觉 2 受体成员 5

种属: Homo sapiens

同用名: T2R5

基因 ID: 54429 | 基因类型: protein coding

关于 TAS2R5

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:141,790,217-141,791,367 (from NCBI)

This gene has 1 transcript (splice variant), 125 orthologues and 23 paralogues.

功能概要

该基因编码苦味受体;苦味受体是 G 蛋白偶联受体超家族的成员,由舌和上颚上皮的味觉受体细胞特异性表达。这些明显无内含子的味觉受体基因中的每一个都编码一个 7 跨膜受体蛋白,作为苦味受体发挥作用。该基因与 7 号染色体上的另外 3 个候选味觉受体基因聚集在一起,并与影响苦味感知的基因座有遗传联系。[RefSeq 提供,2008 年 7 月]

This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by Taste Receptor cells of the tongue and palate epithelia. Each of these apparently intronless Taste Receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter Taste Receptor. This gene is clustered with another 3 candidate Taste Receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]

TAS2R5 基因产物(1)

mRNA Protein Name
NM_018980.3 NP_061853.1 taste receptor type 2 member 5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bitter taste receptor activity IDA
IDA: 通过直接分析推断
20022913 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in detection of chemical stimulus involved in sensory perception of bitter taste IDA
IDA: 通过直接分析推断
20022913 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TAS2R5 蛋白结构

TAS2R

TAS2R: Taste receptor protein (TAS2R) (1 - 290)

  • 0
  • 100
  • 200
  • 299 a.a.
蛋白主名 其他名称

taste receptor type 2 member 5

taste receptor, type 2, member 5

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Waldenstroem'S Macroglobulinemia

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Macroglobulinemia Of Waldenstrom

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Lymphoplasmacytic Lymphoma