2. Gene
  3. ATAD2B - ATPase family AAA domain containing 2B Gene

ATAD2B - ATPase family AAA domain containing 2B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 ATPase 家族 AAA 结构域 2B

种属: Homo sapiens

基因 ID: 54454 | 基因类型: protein coding

关于 ATAD2B

Cytogenetic location: 2p24.1-p23.3 Genomic coordinates (GRCh38): 2:23,677,969-23,927,123 (from NCBI)

This gene has 9 transcripts (splice variants), 214 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 1.9), testis (RPKM 1.9) and 25 other tissues.

功能概要

该基因编码的蛋白质属于 AAA ATPase 家族。该家族成员包括一个 N 端溴结构域。已发现它定位于细胞核，部分定位于复制位点，与染色质相关功能一致。该基因的可变剪接导致多个转录变体。[RefSeq 提供，2014 年 7 月]

The protein encoded by this gene belongs to the AAA ATPase family. This family member includes an N-terminal bromodomain. It has been found to be localized to the nucleus, partly to replication sites, consistent with a chromatin-related function. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2014]

ATAD2B 基因产物(3)

mRNA Protein Name
NM_001242338.3 NP_001229267.2 ATPase family AAA domain-containing protein 2B isoform 2
NM_001354107.2 NP_001341036.1 ATPase family AAA domain-containing protein 2B isoform 3
NM_017552.4 NP_060022.2 ATPase family AAA domain-containing protein 2B isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lysine-acetylated histone binding IDA
IDA: 通过直接分析推断
22464331 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
24561620 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ATAD2B 蛋白结构

AAA

AAA: ATPase family associated with various cellular activities (AAA) (438 - 571)

Bromodomain

Bromodomain: Bromodomain (972 - 1043)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1458 a.a.
蛋白主名 其他名称

ATPase family AAA domain-containing protein 2B

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10326 Z-ATAD-FMK Inhibitor / 否
HY-RS01120 ATAD2B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ATAD2B VGNC VGNC:26234
Canis familiaris ATAD2B VGNC VGNC:38202
Mus musculus ATAD2B MGD MGI:2444798
Felis catus ATAD2B VGNC VGNC:59990
Macaca mulatta ATAD2B VGNC VGNC:106130
Rattus norvegicus ATAD2B RGD RGD:1566199
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