CCHCR1 - coiled-coil alpha-helical rod protein 1 Gene

中文名称：卷曲螺旋α-螺旋杆蛋白 1

种属: Homo sapiens

同用名: HCR; SBP; pg8; C6orf18

关于 CCHCR1

功能概要

该基因编码一种具有五个螺旋螺旋 α 螺旋杆结构域的蛋白质，该结构域被认为通过与 mRNA 脱帽蛋白 4 的相互作用来调节 mRNA 代谢。它定位于 P 体，即 mRNA 代谢的位点，具有此亚细胞定位所需的 N 端，表明它是 P 体成分。该基因中自然发生的突变与牛皮癣有关。[RefSeq 提供，2017 年 5 月]

This gene encodes a protein with five coiled-coil alpha-helical rod domains that is thought to act as a regulator of mRNA metabolism through its interaction with mRNA-decapping protein 4. It localizes to P-bodies, the site of mRNA metabolism, with an N-terminus that is required for this subcellular localization, suggesting it is a P-body component. Naturally occurring mutations in this gene are associated with psoriasis. [provided by RefSeq, May 2017]