2. Gene
  3. EPDR1 - ependymin related 1 Gene

EPDR1 - ependymin related 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：室管膜相关 1

种属: Homo sapiens

同用名: EPDR; UCC1; MERP1; MERP-1

基因 ID: 54749 | 基因类型: protein coding

关于 EPDR1

Cytogenetic location: 7p14.1 Genomic coordinates (GRCh38): 7:37,920,640-37,951,936 (from NCBI)

This gene has 3 transcripts (splice variants) and 489 orthologues. Broad expression in brain (RPKM 25.1), endometrium (RPKM 24.9) and 23 other tissues.

功能概要

由该基因编码的蛋白质是一种 II 型跨膜蛋白，类似于两个细胞粘附分子家族，即原钙粘蛋白和室管膜蛋白。这种蛋白质可能在钙依赖性细胞粘附中起作用。这种蛋白质是糖基化的，直系同源小鼠蛋白质定位于溶酶体。可变剪接导致多个转录本变体。已在 8 号染色体上鉴定出一个相关的假基因。[RefSeq 提供，2011 年 8 月]

The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]

EPDR1 基因产物(3)

mRNA Protein Name
NM_001242946.2 NP_001229875.2 mammalian ependymin-related protein 1 isoform 2 precursor
NM_001242948.2 NP_001229877.1 mammalian ependymin-related protein 1 isoform 3
NM_017549.5 NP_060019.2 mammalian ependymin-related protein 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ganglioside GM1 binding IDA
IDA: 通过直接分析推断
30729188 GOA
enables identical protein binding IDA
IDA: 通过直接分析推断
30729188 GOA
enables phospholipid binding IPI
IPI: 通过物理相互作用推断
30729188 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in myofibroblast contraction IMP
IMP: 通过突变表型推断
27245865 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
30729188 GOA
located in lysosome IDA
IDA: 通过直接分析推断
30729188 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

EPDR1 蛋白结构

Ependymin

Ependymin: Ependymin (81 - 210)

  • 0
  • 100
  • 200
  • 224 a.a.
蛋白主名 其他名称

mammalian ependymin-related protein 1

ependymin related protein 1

重组 EPDR1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70935 EPDR1 Protein, Human (HEK293, His) Q9UM22-1 (A38-S223) ≥95%

关联疾病

疾病名称 别名
Primary Angle-Closure Glaucoma

Primary Angle Closure Glaucoma

Angle Closure Glaucoma

Acg - [Angle Closure Glaucoma]

Angle-Closure Glaucoma

Closed Angle Glaucoma

Acute Glaucoma

Prodromal Angle Closure Glaucoma
Eastern Equine Encephalitis

Eee

Neuroinvasive Eastern Equine Encephalitis Virus Infection

Eastern Equine Encephalomyelitis

Encephalomyelitis, Eastern Equine

Triple E

Eastern Equine Encephalitis Virus Infection

Neuroinvasive Eastern Equine Encephalitis Virus Disease

Eee - [Eastern Equine Encephalitis]
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04421 EPDR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus EPDR1 MGD MGI:2145369
Bos taurus EPDR1 VGNC VGNC:28530
Canis familiaris EPDR1 VGNC VGNC:51868
Macaca mulatta EPDR1 VGNC VGNC:108399
Rattus norvegicus EPDR1 RGD RGD:1359161
Others EPDR1 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z