1. Gene
  2. SNRK - SNF related kinase Gene

SNRK - SNF related kinase Gene

中文名称:SNF 相关激酶

种属: Homo sapiens

同用名: HSNFRK

基因 ID: 54861 | 基因类型: protein coding

关于 SNRK

Cytogenetic location: 3p22.1 Genomic coordinates (GRCh38): 3:43,286,540-43,351,143 (from NCBI)

This gene has 8 transcripts (splice variants), 228 orthologues and 17 paralogues. Ubiquitous expression in bone marrow (RPKM 23.2), thyroid (RPKM 20.1) and 25 other tissues.

功能概要

SNRK 是丝氨酸/苏氨酸激酶的蔗糖非发酵 (SNF) 相关激酶家族的成员 (Kertesz 等人,2002 [PubMed 12234663]) 。[OMIM 提供,2009 年 4 月]

SNRK is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases (Kertesz et al., 2002 [PubMed 12234663]).[supplied by OMIM, Apr 2009]

SNRK 基因产物(3)

mRNA Protein Name
NM_001100594.2 NP_001094064.1 SNF-related serine/threonine-protein kinase isoform 1
NM_001330750.2 NP_001317679.1 SNF-related serine/threonine-protein kinase isoform 2
NM_017719.5 NP_060189.3 SNF-related serine/threonine-protein kinase isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
12234663 GOA
enables magnesium ion binding IDA
IDA: 通过直接分析推断
12234663 GOA
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
12234663 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein phosphorylation IDA
IDA: 通过直接分析推断
12234663 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SNRK 蛋白结构

Pkinase

Pkinase: Protein kinase domain (16 - 269)

  • 0
  • 200
  • 400
  • 600
  • 765 a.a.
蛋白主名 其他名称

SNF-related serine/threonine-protein kinase

SNF-1 related kinase

关联疾病

疾病名称 别名
Skin Angiosarcoma

Angiosarcoma Of Skin

Hemangiosarcoma Of The Skin

Haemangiosarcoma Of Skin

Lymphangiosarcoma Of Skin

Cutaneous Angiosarcoma

Malignant Haemangioendothelioma Of Skin

Liver Angiosarcoma

Angiosarcoma Of Liver

Angiosarcoma Of The Liver

Hemangiosarcoma Of The Liver

Primary Angiosarcoma Of Liver

Kupffer Cell Sarcoma Of Liver

Kupffer Cell Sarcoma Of Unspecified Site

Neuronopathy, Distal Hereditary Motor, Type Viii

Autosomal Dominant Congenital Benign Spinal Muscular Atrophy

HMN8

Dhmn8

Neuropathy, Distal Hereditary Motor, Type Viii

Distal Hereditary Motor Neuronopathy Type 8

Autosomal Dominant Benign Distal Spinal Muscular Atrophy

Congenital Benign Spinal Muscular Atrophy With Contractures

Congenital Nonprogressive Spinal Muscular Atrophy

Spinal Muscular Atrophy, Distal, Congenital Nonprogressive

Spinal Muscular Atrophy, Congenital Benign, With Contractures

Distal Hereditary Motor Neuropathy Type Viii

Neuronopathy, Distal Hereditary Motor, 8

Distal Spinal Muscular Atrophy, Congenital Non-Progressive

Spinal Muscular Atrophy Congenital Benign With Contractures

Breast Angiosarcoma

Angiosarcoma Of The Breast

Hemangiosarcoma Of The Breast

Primary Angiosarcoma Of Breast

Skin Sarcoma

Cutaneous Sarcoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SNRK RGD RGD:69653
Macaca mulatta SNRK VGNC VGNC:84074
Canis familiaris SNRK VGNC VGNC:54995
Mus musculus SNRK MGD MGI:108104
Bos taurus SNRK VGNC VGNC:50156
Felis catus SNRK VGNC VGNC:65531
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