DPP8 - dipeptidyl peptidase 8 Gene

中文名称：二肽基肽酶 8

种属: Homo sapiens

同用名: DP8; DPRP1; DPRP-1; MST097; MSTP097; MSTP135; MSTP141

关于 DPP8

功能概要

该基因编码肽酶 S9B 家族的一个成员，这是一个二肽基肽酶家族，能够在脯氨酰键处切割肽底物。编码的蛋白质与二肽基肽酶 IV 具有相似性，因为它普遍表达并水解相同的底物。这些相似之处表明，与二肽基肽酶 IV 一样，这种蛋白质可能在 T 细胞激活和免疫功能中发挥作用。已经描述了编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with Dipeptidyl Peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like Dipeptidyl Peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]