1. Gene
  2. NPY4R - neuropeptide Y receptor Y4 Gene

NPY4R - neuropeptide Y receptor Y4 Gene

中文名称:神经肽 Y 受体 Y4

种属: Homo sapiens

同用名: Y4; PP1; PPYR1; NPY4-R

基因 ID: 5540 | 基因类型: protein coding

关于 NPY4R

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:46,461,099-46,470,668 (from NCBI)

This gene has 2 transcripts (splice variants), 115 orthologues and 33 paralogues. Biased expression in colon (RPKM 2.9), skin (RPKM 1.7) and 7 other tissues.

功能概要

启用胰多肽受体活性和肽激素结合活性。参与 G 蛋白偶联受体信号通路。位于膜内。 [由基因组资源联盟提供,2022 年 4 月]

Enables pancreatic polypeptide receptor activity and peptide hormone binding activity. Involved in G protein-coupled receptor signaling pathway. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

NPY4R 基因产物(10)

mRNA Protein Name
NM_001278794.2 NP_001265723.1 neuropeptide Y receptor type 4
XM_017016386.3 XP_016871875.1 neuropeptide Y receptor type 4 isoform X1
NM_005972.6 NP_005963.4 neuropeptide Y receptor type 4
XM_011539937.4 XP_011538239.1 neuropeptide Y receptor type 4 isoform X1
XR_001747124.3
XM_011539936.4 XP_011538238.1 neuropeptide Y receptor type 4 isoform X1
XR_007061972.1
XM_017016387.3 XP_016871876.1 neuropeptide Y receptor type 4 isoform X1
NM_001278794.2 NP_001265723.1 neuropeptide Y receptor type 4
NM_005972.6 NP_005963.4 neuropeptide Y receptor type 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables pancreatic polypeptide receptor activity IDA
IDA: 通过直接分析推断
7493937 GOA
enables peptide hormone binding IPI
IPI: 通过物理相互作用推断
7493937 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
7592911 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
7493937 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NPY4R 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (58 - 322)

  • 0
  • 100
  • 200
  • 300
  • 375 a.a.
蛋白主名 其他名称

neuropeptide Y receptor type 4

pancreatic polypeptide receptor 1

关联疾病

疾病名称 别名
Postsurgical Hypothyroidism

Postoperative Hypothyroidism

Post-Surgical Hypothyroidism

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus NPY4R MGD MGI:105374
Rattus norvegicus NPY4R RGD RGD:61864