TNFRSF19 - TNF receptor superfamily member 19 Gene

中文名称：TNF 受体超家族成员 19

种属: Homo sapiens

同用名: TAJ; TROY; TRADE; TAJ-alpha

基因 ID: 55504 | 基因类型: protein coding

关于 TNFRSF19

Cytogenetic location: 13q12.12 Genomic coordinates (GRCh38): 13:23,570,412-23,676,093 (from NCBI)

This gene has 5 transcripts (splice variants), 209 orthologues and 2 paralogues. Biased expression in skin (RPKM 37.6), prostate (RPKM 12.9) and 8 other tissues.

功能概要

由该基因编码的蛋白质是 TNF 受体超家族的成员。该受体在胚胎发育过程中高度表达。它已被证明与 TRAF 家族成员相互作用，并在细胞中过表达时激活 JNK 信号通路。该受体能够通过半胱天冬酶非依赖性机制诱导细胞凋亡，并且被认为在胚胎发育中发挥重要作用。已经描述了编码不同同种型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing Apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

TNFRSF19 基因产物(5)

mRNA	Protein	Name
NM_001204458.3	NP_001191387.1	tumor necrosis factor receptor superfamily member 19 isoform 2 precursor
NM_001204459.2	NP_001191388.1	tumor necrosis factor receptor superfamily member 19 isoform 3
NM_001354985.2	NP_001341914.1	tumor necrosis factor receptor superfamily member 19 isoform 4 precursor
NM_018647.5	NP_061117.2	tumor necrosis factor receptor superfamily member 19 isoform 1 precursor
NM_148957.4	NP_683760.1	tumor necrosis factor receptor superfamily member 19 isoform 2 precursor

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	30337686	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

tumor necrosis factor receptor superfamily member 19

toxicity and JNK inducer

TNFRSF19 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TNFRSF19	Q9NS68	PHB1	Homo sapiens	P35232	Anti Bait CoIP	30337686
种属内	TNFRSF19	Q9NS68	PHB1	Homo sapiens	P35232	IF	30337686
种属内	TNFRSF19	Q9NS68	ARHGDIA	Homo sapiens	P52565	IF	30337686
种属内	TNFRSF19	Q9NS68	ARHGDIA	Homo sapiens	P52565	Anti Bait CoIP	30337686
种属内	TNFRSF19	Q9NS68	PEBP1	Homo sapiens	P30086	IF	30337686
种属内	TNFRSF19	Q9NS68	PEBP1	Homo sapiens	P30086	Anti Bait CoIP	30337686

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 TNFRSF19 蛋白

目录号	产品名	蛋白编号	纯度
HY-P73572	TROY/TNFRSF19 Protein, Human (HEK293, His)	Q9NS68-2 (E30-L170)	≥95%
HY-P73573	TROY/TNFRSF19 Protein, Human (HEK293, Fc)	Q9NS68-2 (M1-L170)	≥95%

TNFRSF19 抗体

目录号	产品名	应用	反应物种
HY-P83120	TNFRSF19 Antibody (YA2865)	WB, IHC-P, FC	Human, Mouse, Rat

关联疾病

疾病名称

别名

Ovarian Cancer

Ovarian Carcinoma	Ovarian Neoplasm
Malignant Tumour Of Ovary	Cancer Of The Ovary
Epithelial Ovarian Cancer	Neoplasm Of Ovary
Ovarian Neoplasms	Ovarian Cancers
Malignant Neoplasm Of Ovary	Primary Malignant Neoplasm Of Ovary
Ovarian Cancer, Somatic	Malignant Ovarian Tumor
Ovary Neoplasm	Primary Ovarian Cancer
Tumor Of The Ovary	Malignant Neoplasm Of The Ovary
Malignant Tumor Of The Ovary	Ovarian Malignant Tumor
OC	Ovarian Carcinomas
Cancer, Ovarian	Cancer Of Ovary
Ovary Cancer	Ca Ovary

Ectodermal Dysplasia

Congenital Ectodermal Defect	Congenital Ectodermal Dysplasia
Ectodermal Dysplasia Syndrome	Dysplasia, Ectodermal

Ectodermal Dysplasia 10b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive

Hypohidrotic Ectodermal Dysplasia	Hed
Anhidrotic Ectodermal Dysplasia	Ectodermal Dysplasia, Hypohidrotic
Eda	Christ-Siemens-Touraine Syndrome
ECTD10B	Ectodermal Dysplasia Anhidrotic
Ectodermal Dysplasia, Anhidrotic	Cst Syndrome
Ectodermal Dysplasia Hypohidrotic Autosomal Recessive	Dysplasia, Ectodermal, Type 10b, Hypohidrotic/Hair/Tooth, Autosomal Recessive
Dysplasia, Ectodermal, Hypohidrotic	Ectodermal Dysplasia 11b, Hypohidrotic/Hair/Tooth Type, Autosomal Recessive
Ectodermal Dysplasia 3, Anhidrotic	Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14809	TNFRSF19 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	TNFRSF19	MGD	MGI:1352474
Bos taurus	TNFRSF19	VGNC	VGNC:53840
Canis familiaris	TNFRSF19	VGNC	VGNC:47661
Felis catus	TNFRSF19	VGNC	VGNC:66407
Rattus norvegicus	TNFRSF19	RGD	RGD:1564996
Macaca mulatta	TNFRSF19	VGNC	VGNC:78588
Others	TNFRSF19	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

TNFRSF19 - TNF receptor superfamily member 19 Gene

关于 TNFRSF19

功能概要

TNFRSF19 基因产物(5)

TNFRSF19 蛋白互作信息

重组 TNFRSF19 蛋白

TNFRSF19 抗体

关联疾病

直系同源

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TNFRSF19 - TNF receptor superfamily member 19 Gene

关于 TNFRSF19

功能概要

TNFRSF19 基因产物(5)

TNFRSF19 蛋白互作信息

重组 TNFRSF19 蛋白

TNFRSF19 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z