2. Gene
  3. TRPV5 - transient receptor potential cation channel subfamily V member 5 Gene

TRPV5 - transient receptor potential cation channel subfamily V member 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：瞬时受体电位阳离子通道亚家族 V 成员 5

种属: Homo sapiens

同用名: CAT2; ECAC1; OTRPC3

基因 ID: 56302 | 基因类型: protein coding

关于 TRPV5

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:142,908,101-142,933,746 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 101 orthologues and 5 paralogues. Low expression observed in reference dataset.

功能概要

该基因是瞬时受体家族和 TRPV 亚家族的成员。该基因编码的钙选择性通道具有 6 个跨膜结构域、多个潜在磷酸化位点、一个 N-连接糖基化位点和 5 个 ANK 重复序列。这种蛋白质形成同源四聚体或异源四聚体，并被低内部钙水平激活。[RefSeq 提供，2008 年 7 月]

This gene is a member of the transient receptor family and the TRPV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]

TRPV5 基因产物(1)

mRNA Protein Name
NM_019841.7 NP_062815.3 transient receptor potential cation channel subfamily V member 5

TRPV5 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (121 - 208)

Ion_trans

Ion_trans: Ion transport protein (417 - 578)

  • 0
  • 200
  • 400
  • 600
  • 729 a.a.
蛋白主名 其他名称

transient receptor potential cation channel subfamily V member 5

calcium transport protein 2

TRPV5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TRPV5 Q9NQA5 CALB1 Homo sapiens P05937
Pull Down
16763551
种属间: 跨种属相互作用 种属内: 同种属相互作用

TRPV5 抗体

目录号 产品名 应用 反应物种
HY-P82539 TrpV5 Antibody (YA2284) WB, IP Human, Mouse, Rat

关联疾病

疾病名称 别名
Urolithiasis
Pseudohypoaldosteronism
Scapuloperoneal Spinal Muscular Atrophy

SPSMA

Amyotrophy, Neurogenic Scapuloperoneal, New England Type

Neurogenic Scapuloperoneal Amyotrophy, New England Type

Scapuloperoneal Neuronopathy

Spinal Muscular Atrophy, Scapuloperoneal

Amyotrophy Neurogenic Scapuloperoneal New England Type

Muscular Atrophy, Spinal

Scapuloperoneal Form Of Spinal Muscular Atrophy
Hypervitaminosis D

Vitamin D Hyperalimentation
Nephrolithiasis

Kidney Stones

Stone - Kidney/Ureter

Kidney Calculi
Mutilating Palmoplantar Keratoderma With Periorificial Keratotic Plaques

Olmsted Syndrome

Mutilating Palmoplantar Hyperkeratosis With Periorificial Keratotic Plaques

Palmoplantar And Periorificial Keratoderma

Olms
Metatropic Dysplasia

Metatropic Dwarfism

MTD

Metatropic Dysplasia Type 1

Metatropic Dysplasia, Nonlethal Dominant
Skin Atrophy

Atrophic Condition Of Skin

Atrophoderma

Atrophy - Skin
Familial Hypocalciuric Hypercalcemia

Familial Benign Hypercalcemia

Fbh

Fbhh

Fhh

Familial Benign Hypocalciuric Hypercalcemia

Hypocalciuric Hypercalcemia, Familial, Type 1
Mucolipidosis Iv

Mucolipidosis Type Iv

ML4

Sialolipidosis

Mucolipidosis Type 4

Ganglioside Sialidase Deficiency

Mliv

Ml Iv

Berman Syndrome

Ganglioside Neuraminidase Deficiency

Ml 4

Mucolipidosis 4

Type Iv Mucolipidosis

Gangliosidoses
Phosphorus Metabolism Disease

Phosphorus Metabolism Disorders

Disorder Of Phosphorus Metabolism

Phosphorus Disorder

Phosphorus Metabolism Disorder
Schnyder Corneal Dystrophy

Schnyder Crystalline Corneal Dystrophy

SCCD

Corneal Dystrophy, Crystalline, Of Schnyder

Corneal Dystrophy, Schnyder Type

Corneal Dystrophy Crystalline Of Schnyder

Crystalline Stromal Dystrophy

Hereditary Crystalline Stromal Dystrophy Of Schnyder

Scd

Corneal Dystrophy, Schnyder

Schnyder Crystalline Dystrophy Sine Crystals

Dystrophy, Corneal, Crystalline, Schnyder
Parathyroid Gland Disease

Parathyroid Diseases

Disease Of Parathyroid Glands

Parathyroid Disease
Bartter Disease

Bartter Syndrome

Bartter'S Syndrome

Aldosteronism With Hyperplasia Of The Adrenal Cortex

Hypokalemic Alkalosis With Hypercalciuria

Potassium Wasting

Juxtaglomerular Hyperplasia With Secondary Aldosteronism

Renal Tubular Normotensive Hypokalemic Alkalosis With Hypercalciuria

Salt-Losing Tubular Disorder, Henle'S Loop Type

Salt-Wasting Tubulopathy, Henle'S Loop Type

Bartters Syndrome
Vertigo, Benign Recurrent

Benign Paroxysmal Positional Vertigo

Bppv

Vestibulopathy, Familial

BRV

Vertigo, Benign Paroxysmal Positional

Benign Paroxysmal Positional Nystagmus

Benign Recurrent Vertigo

Familial Benign Recurrent Vertigo

Familial Vestibulopathy

Benign Paroxysmal Nystagmus

Bppv - [Benign Positional Paroxysmal Vertigo]
Pseudohypoparathyroidism, Type Ib

Pseudohypoparathyroidism Type 1b

PHP1B

Pseudohypoparathyroidism Ib

Pseudohypoparathyroidism Type Ib

Php Ib

Pseudohypoparathyroidism 1b
Autosomal Dominant Polycystic Kidney Disease

Polycystic Kidney Disease, Adult Type

Adpkd

Polycystic Kidney Diseases

Polycystic Kidney, Autosomal Dominant

Congenital Biliary Ectasias

Polycystic Kidney And Hepatic Disease 1

Polycystic Kidney Disease, Autosomal Dominant

Kidney, Polycystic, Disease, Autosomal Dominant

Adult Polycystic Kidney Disease

Polycystic Kidney, Adult Type

Apckd - [Autosomal Polycystic Kidney Disease]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15125 TRPV5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TRPV5 VGNC VGNC:36401
Macaca mulatta TRPV5 VGNC VGNC:81783
Mus musculus TRPV5 MGD MGI:2429764
Felis catus TRPV5 VGNC VGNC:66599
Canis familiaris TRPV5 VGNC VGNC:47885
Rattus norvegicus TRPV5 RGD RGD:620636
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