1. Gene
  2. Tacstd2 - tumor-associated calcium signal transducer 2 Gene

Tacstd2 - tumor-associated calcium signal transducer 2 Gene

种属: Mus musculus

同用名: Ly97; EGP-1; TROP2; GA733-1

基因 ID: 56753 | 基因类型: protein coding

关于 Tacstd2

功能概要

Involved in several processes, including negative regulation of branching involved in ureteric bud morphogenesis; negative regulation of cellular component organization; and negative regulation of substrate adhesion-dependent cell spreading. Acts upstream of or within positive regulation of stem cell differentiation; regulation of epithelial cell proliferation; and ureteric bud morphogenesis. Located in several cellular components, including basal plasma membrane; extracellular space; and lateral plasma membrane. Is expressed in alimentary system; genitourinary system; sensory organ; and skin. Human ortholog(s) of this gene implicated in corneal dystrophy and gelatinous drop-like corneal dystrophy. Orthologous to human TACSTD2 (tumor associated calcium signal transducer 2). [provided by Alliance of Genome Resources, Apr 2022]

Tacstd2 基因产物(1)

mRNA Protein Name
NM_020047.3 NP_064431.2 tumor-associated calcium signal transducer 2 precursor
基因本体论
  • 生物过程
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal plasma membrane IDA
IDA: 通过直接分析推断
22194864 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
23070813 MGI
located in lateral plasma membrane IDA
IDA: 通过直接分析推断
22194864 MGI
located in membrane IDA
IDA: 通过直接分析推断
23070813 MGI
located in nucleus IDA
IDA: 通过直接分析推断
23070813 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9462726 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tumor-associated calcium signal transducer 2

cell surface glycoprotein Trop-2

lymphocyte antigen 97

tunor-associated calcium signal transducer 2

重组 Tacstd2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71387 TROP-2 Protein, Mouse (246a.a, HEK293, His) Q8BGV3 (Q25-G270) ≥95%
HY-P74488 TROP-2 Protein, Mouse (HEK293, hFc) Q8BGV3 (Q25-Q270) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tacstd2 NCBI NCBI:4070
Macaca fascicularis Tacstd2 NCBI NCBI:102127436
Rattus norvegicus Tacstd2 NCBI NCBI:494343
Macaca mulatta Tacstd2 NCBI NCBI:716334