2. 重组蛋白
  3. CAR-T related Proteins
  4. TROP-2
  5. TROP-2 蛋白, Mouse (HEK293, hFc)

TROP-2 蛋白, Mouse (HEK293, hFc)

目录号: HY-P74488
产品使用指南

TROP-2 蛋白作为生长因子受体发挥作用，并已被证明在介导与生长调节相关的细胞反应中发挥着关键作用。它的参与表明它在细胞生长过程中的信号转导中发挥着至关重要的作用。TROP-2 蛋白, Mouse (HEK293, hFc) 是重组的 TROP-2 蛋白，由 HEK293 表达，带有 C-hFc 标签。TROP-2 蛋白, Mouse (HEK293, hFc) 全长 246 个氨基酸，分子量约为 ~66 kDa。

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描述

The TROP-2 protein functions as a growth factor receptor and has been shown to play a critical role in mediating cellular responses associated with growth regulation. Its involvement indicates that it plays a crucial role in signal transduction during cell growth. TROP-2 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived TROP-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TROP-2 Protein, Mouse (HEK293, hFc) is 246 a.a., with molecular weight of ~66 kDa.
研究背景

TROP-2 蛋白似乎具有生长因子受体的功能，这表明在介导与生长调节相关的细胞反应中发挥着关键作用。TROP-2 参与这种能力表明 TROP-2 可能在细胞生长过程的信号转导中发挥着至关重要的作用。进一步探索 TROP-2 作为生长因子受体介导的特定信号通路和下游效应，可以为了解其功能意义以及对细胞发育和稳态的潜在影响提供有价值的见解。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

Q8BGV3 (Q25-Q270)
基因 ID
蛋白结构
N-term
TROP-2 (Q25-Q270)
Accession # Q8BGV3
hFc
C-term
同用名
Tumor-associated calcium signal transducer 2; Cell surface glycoprotein Trop-2; TACSTD2; TROP2
分子量

Approximately 66 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

TROP-2 Protein, Mouse (HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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