DHX33 - DEAH-box helicase 33 Gene

中文名称：DEAH 盒解旋酶 33

种属: Homo sapiens

同用名: DDX33

关于 DHX33

功能概要

该基因编码 DEAD box 蛋白家族的一个成员。 DEAD 盒蛋白的特征在于保守基序 Asp-Glu-Ala-Asp (DEAD) ，是推定的 RNA 解旋酶。它们涉及许多涉及 RNA 二级结构改变的细胞过程，例如翻译起始、核和线粒体剪接以及核糖体和剪接体组装。根据它们的分布模式，该 DEAD 盒蛋白家族的一些成员被认为参与了胚胎发生、精子发生以及细胞生长和分裂。可变剪接导致多个转录本变体。[RefSeq 提供，2010 年 12 月]

This gene encodes a member of the DEAD box protein family. The DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]