CEMIP - cell migration inducing hyaluronidase 1 Gene

中文名称：细胞迁移诱导透明质酸酶 1

种属: Homo sapiens

同用名: CCSP1; HYBID; TMEM2L; KIAA1199

基因 ID: 57214 | 基因类型: protein coding

关于 CEMIP

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:80,779,370-80,951,771 (from NCBI)

This gene has 6 transcripts (splice variants), 198 orthologues and 1 paralogue. Biased expression in endometrium (RPKM 32.4), appendix (RPKM 6.2) and 5 other tissues.

功能概要

启用多种功能，包括网格蛋白重链结合活性；透明质酸结合活性；和透明质酸非葡糖胺酶活性。参与多个过程，包括乙酰透明质酸分解代谢过程；蛋白质磷酸化的正调节；和运输的积极监管。位于网格蛋白包被的内吞囊泡中；内质网；和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including clathrin heavy chain binding activity; hyaluronic acid binding activity; and hyalurononglucosaminidase activity. Involved in several processes, including hyaluronan catabolic process; positive regulation of protein phosphorylation; and positive regulation of transport. Located in clathrin-coated endocytic vesicle; endoplasmic reticulum; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CEMIP 基因产物(3)

mRNA	Protein	Name
NM_001293298.2	NP_001280227.1	cell migration-inducing and hyaluronan-binding protein precursor
NM_001293304.2	NP_001280233.1	cell migration-inducing and hyaluronan-binding protein precursor
NM_018689.3	NP_061159.1	cell migration-inducing and hyaluronan-binding protein precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables ER retention sequence binding	IDA IDA: 通过直接分析推断	23990668	GOA
enables clathrin heavy chain binding	IDA IDA: 通过直接分析推断	23509262	GOA
enables hyaluronic acid binding	IDA IDA: 通过直接分析推断	23509262	GOA
enables hyalurononglucosaminidase activity	IMP IMP: 通过突变表型推断	23509262	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	23990668	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in hyaluronan catabolic process	IMP IMP: 通过突变表型推断	23509262	GOA
involved in positive regulation of cell migration	IDA IDA: 通过直接分析推断	23990668	GOA
involved in positive regulation of peptidyl-threonine phosphorylation	IDA IDA: 通过直接分析推断	23990668	GOA
involved in positive regulation of protein kinase C activity	IDA IDA: 通过直接分析推断	23990668	GOA
involved in positive regulation of protein targeting to membrane	IDA IDA: 通过直接分析推断	23990668	GOA
involved in positive regulation of release of sequestered calcium ion into cytosol	IDA IDA: 通过直接分析推断	23990668	GOA
involved in sensory perception of sound	IMP IMP: 通过突变表型推断	14577002	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in clathrin-coated endocytic vesicle	IDA IDA: 通过直接分析推断	23509262	GOA
located in cytoplasm	IDA IDA: 通过直接分析推断	16157444	GOA
located in cytoplasm	IMP IMP: 通过突变表型推断	14577002	GOA
located in endoplasmic reticulum	IDA IDA: 通过直接分析推断	23990668	GOA
located in plasma membrane	IDA IDA: 通过直接分析推断	23509262	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CEMIP 蛋白结构

Mucin2_WxxW

0
300
600
900
1200
1361 a.a.

蛋白主名

其他名称

cell migration-inducing and hyaluronan-binding protein

cell migration inducing hyaluronan binding protein

关联疾病

疾病名称

别名

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式 Pre-designed Sets	纯度	是否罕见病否
HY-RS02468	CEMIP Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS02469	CEMIP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Canis familiaris	CEMIP	VGNC	VGNC:39099
Macaca mulatta	CEMIP	VGNC	VGNC:71130
Felis catus	CEMIP	VGNC	VGNC:60750
Bos taurus	CEMIP	VGNC	VGNC:27172
Mus musculus	CEMIP	MGD	MGI:2443629
Rattus norvegicus	CEMIP	RGD	RGD:1305254

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CEMIP - cell migration inducing hyaluronidase 1 Gene

关于 CEMIP

功能概要

CEMIP 基因产物(3)

CEMIP 蛋白结构

关联疾病

直系同源

热门区域

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CEMIP - cell migration inducing hyaluronidase 1 Gene

关于 CEMIP

功能概要

CEMIP 基因产物(3)

CEMIP 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z