S100A14 - S100 calcium binding protein A14 Gene

中文名称：S100 钙结合蛋白 A14

种属: Homo sapiens

同用名: BCMP84; S100A15

基因 ID: 57402 | 基因类型: protein coding

关于 S100A14

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,614,255-153,616,325 (from NCBI)

This gene has 6 transcripts (splice variants), 355 orthologues and 21 paralogues. Biased expression in esophagus (RPKM 798.1), skin (RPKM 171.2) and 6 other tissues.

功能概要

该基因编码 S100 蛋白家族的一个成员，该家族包含一个 EF 手基序并结合钙。该基因位于 1 号染色体上的一组 S100 基因中。已发现编码蛋白的水平在癌组织中较低，并且与转移相关，表明具有肿瘤抑制功能 (PMID：19956863、19351828) 。[RefSeq 提供，2011 年 12 月]

This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011]

S100A14 基因产物(1)

mRNA	Protein	Name
NM_020672.3	NP_065723.1	protein S100-A14

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables chemokine receptor binding	IMP IMP: 通过突变表型推断	18606705	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	16189514	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in defense response to bacterium	IEP IEP: 通过表达模式推断	17625598	GOA
involved in positive regulation of granulocyte chemotaxis	IDA IDA: 通过直接分析推断	18606705	GOA
involved in positive regulation of monocyte chemotaxis	IDA IDA: 通过直接分析推断	18606705	GOA
involved in response to lipopolysaccharide	IEP IEP: 通过表达模式推断	17625598	GOA
involved in toll-like receptor 4 signaling pathway	IDA IDA: 通过直接分析推断	17625598	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in perinuclear region of cytoplasm	IDA IDA: 通过直接分析推断	11944983	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

S100A14 蛋白结构

S_100

0
104 a.a.

蛋白主名

其他名称

protein S100-A14

S114

S100A14 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	S100A14	Q9HCY8	MAGEA6	Homo sapiens	P43360	Validated Y2H	25416956
种属内	S100A14	Q9HCY8	MAGEA6	Homo sapiens	P43360	Y2H Array	25416956
种属内	S100A14	Q9HCY8	MAGEA6	Homo sapiens	P43360	Y2H Prey Pooling	25416956
种属内	S100A14	Q9HCY8	S100A16	Homo sapiens	Q96FQ6	Validated Y2H	25416956
种属内	S100A14	Q9HCY8	S100A16	Homo sapiens	Q96FQ6	Y2H Prey Pooling	25416956
种属内	S100A14	Q9HCY8	S100A16	Homo sapiens	Q96FQ6	Y2H Array	25416956
种属内	S100A14	Q9HCY8	S100A16	Homo sapiens	Q96FQ6	Y2H Pooling	16189514

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 S100A14 蛋白

目录号	产品名	蛋白编号	纯度
HY-P76584	S100A14 Protein, Human (His)	Q9HCY8.1 (G2-H104)	≥95%

关联疾病

疾病名称

别名

Trachea Leiomyoma

Tracheal Neoplasms	Leiomyoma Of The Trachea
Tracheal Neoplasm	Tracheal Leiomyoma

Small Intestine Adenocarcinoma

Small Intestinal Adenocarcinoma	Adenocarcinoma Of Small Intestine
Adenocarcinoma Of The Small Bowel	Adenocarcinoma Of Small Bowel
Adenocarcinoma Of Small Instestine	Adenocarcinoma Of The Small Instestine
Small Bowel Adenocarcinoma	Adenocarcinoma Of The Small Intestine

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12376	S100A14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	S100A14	VGNC	VGNC:34240
Mus musculus	S100A14	MGD	MGI:1913416
Canis familiaris	S100A14	VGNC	VGNC:45826
Felis catus	S100A14	VGNC	VGNC:64839
Rattus norvegicus	S100A14	RGD	RGD:1595063
Others	S100A14	NCBI

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

S100A14 - S100 calcium binding protein A14 Gene

关于 S100A14

功能概要

S100A14 基因产物(1)

S100A14 蛋白结构

S100A14 蛋白互作信息

重组 S100A14 蛋白

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

S100A14 - S100 calcium binding protein A14 Gene

关于 S100A14

功能概要

S100A14 基因产物(1)

S100A14 蛋白结构

S100A14 蛋白互作信息

重组 S100A14 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z