1. Gene
  2. NLN - neurolysin Gene

NLN - neurolysin Gene

中文名称:神经溶解素

种属: Homo sapiens

同用名: MEP; MOP; AGTBP; EP24.16

基因 ID: 57486 | 基因类型: protein coding

关于 NLN

Cytogenetic location: 5q12.3 Genomic coordinates (GRCh38): 5:65,722,205-65,829,283 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 2 paralogues. Ubiquitous expression in liver (RPKM 3.9), brain (RPKM 3.5) and 25 other tissues.

功能概要

该基因编码金属肽酶 M3 蛋白家族的一个成员,该家族在 Pro10-Tyr11 键处切割神经降压素,从而导致神经降压素 (1-10) 和神经降压素 (11-13) 的形成。编码的蛋白质可能参与中枢神经系统和胃肠道中神经降压素信号的终止。[RefSeq 提供,2010 年 6 月]

This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]

NLN 基因产物(1)

mRNA Protein Name
NM_020726.5 NP_065777.1 neurolysin, mitochondrial

NLN 蛋白结构

Peptidase_M3

Peptidase_M3: Peptidase family M3 (251 - 700)

  • 0
  • 200
  • 400
  • 600
  • 704 a.a.
蛋白主名 其他名称

neurolysin, mitochondrial

angiotensin binding protein

重组 NLN 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75938 Neurolysin Protein, Human (His) Q9BYT8 (S38-P704) ≥95%

关联疾病

疾病名称 别名
Senile Ectropion

Involutional Ectropion

Astigmatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NLN RGD RGD:621518
Macaca mulatta NLN VGNC VGNC:75183
Felis catus NLN VGNC VGNC:63825
Mus musculus NLN MGD MGI:1923055
Bos taurus NLN VGNC VGNC:97293
Canis familiaris NLN VGNC VGNC:43842
Others NLN NCBI