2. Gene
  3. GRAMD1A - GRAM domain containing 1A Gene

GRAMD1A - GRAM domain containing 1A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 GRAM 结构域 1A

种属: Homo sapiens

同用名: KIAA1533

基因 ID: 57655 | 基因类型: protein coding

关于 GRAMD1A

This gene has 15 transcripts (splice variants), 191 orthologues and 4 paralogues. Ubiquitous expression in lung (RPKM 13.7), spleen (RPKM 13.3) and 25 other tissues.

功能概要

预测可启用胆固醇结合活性和胆固醇转移活性。预计参与细胞对胆固醇的反应。位于胞质溶胶中；细胞器膜接触部位；和质膜。是质膜细胞质侧的外在成分和内质网膜的内在成分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Cholesterol binding activity and Cholesterol transfer activity. Predicted to be involved in cellular response to Cholesterol. Located in cytosol; organelle membrane contact site; and plasma membrane. Is extrinsic component of cytoplasmic side of plasma membrane and intrinsic component of endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

GRAMD1A 基因产物(5)

mRNA Protein Name
NM_001136199.3 NP_001129671.1 protein Aster-A isoform 2
NM_001320034.2 NP_001306963.1 protein Aster-A isoform 3
NM_001320035.2 NP_001306964.1 protein Aster-A isoform 4
NM_001320036.2 NP_001306965.1 protein Aster-A isoform 5
NM_020895.5 NP_065946.2 protein Aster-A isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
29469807 GOA
located in organelle membrane contact site IDA
IDA: 通过直接分析推断
29469807 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
29469807 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GRAMD1A 蛋白结构

GRAM

GRAM: GRAM domain (91 - 157)

  • 0
  • 200
  • 400
  • 600
  • 724 a.a.
蛋白主名 其他名称

protein Aster-A

GRAM domain-containing protein 1A

关联疾病

疾病名称 别名
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05772 GRAMD1A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta GRAMD1A VGNC VGNC:73029
Canis familiaris GRAMD1A VGNC VGNC:41465
Bos taurus GRAMD1A VGNC VGNC:29622
Mus musculus GRAMD1A MGD MGI:105490
Rattus norvegicus GRAMD1A RGD RGD:1311022
Felis catus GRAMD1A VGNC VGNC:62701
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