1. Gene
  2. Trem1 - triggering receptor expressed on myeloid cells 1 Gene

Trem1 - triggering receptor expressed on myeloid cells 1 Gene

种属: Mus musculus

基因 ID: 58217 | 基因类型: protein coding

关于 Trem1

功能概要

Predicted to enable scaffold protein binding activity. Acts upstream of or within neutrophil chemotaxis; neutrophil extravasation; and neutrophil-mediated killing of gram-negative bacterium. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in bladder and renal vasculature. Human ortholog(s) of this gene implicated in Bacterial pneumonia; Bacterial sepsis; malaria; and myocardial infarction. Orthologous to human TREM1 (triggering receptor expressed on myeloid cells 1). [provided by Alliance of Genome Resources, Apr 2022]

Trem1 基因产物(2)

mRNA Protein Name
NM_001347399.1 NP_001334328.1 triggering receptor expressed on myeloid cells 1 isoform 2 precursor
NM_021406.5 NP_067381.1 triggering receptor expressed on myeloid cells 1 isoform 1 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within chemokine production IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within cytokine production IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within cytokine production involved in immune response IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within neutrophil chemotaxis IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within neutrophil extravasation IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within neutrophil migration IGI
IGI: 通过遗传相互作用推断
23241959 MGI
acts upstream of or within neutrophil-mediated killing of gram-negative bacterium IGI
IGI: 通过遗传相互作用推断
23241959 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

triggering receptor expressed on myeloid cells 1

triggering receptor expressed in monocytes 1

重组 Trem1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70716 TREM-1 Protein, Mouse (HEK293, His) Q9JKE2 (A21-S202) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trem1 NCBI NCBI:54210