2. Gene
  3. Nectin1 - nectin cell adhesion molecule 1 Gene

Nectin1 - nectin cell adhesion molecule 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PRR; HIgR; HveC; PRR1; Cd111; Pvrl1; nectin-1

基因 ID: 58235 | 基因类型: protein coding

关于 Nectin1

功能概要

Enables protein homodimerization activity and signaling receptor activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within several processes, including camera-type eye development; desmosome organization; and enamel mineralization. Located in adherens junction; apical junction complex; and cell-cell contact zone. Is active in hippocampal mossy fiber to CA3 synapse. Is integral component of presynaptic active zone membrane. Is expressed in brain; oral region epithelium; sensory organ; skin; and upper jaw molar. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Nectin1 基因产物(1)

mRNA Protein Name
NM_021424.3 NP_067399.2 nectin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12826663 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
12826663 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
11090177 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within camera-type eye morphogenesis IMP
IMP: 通过突变表型推断
15728677 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: 通过突变表型推断
18703497 MGI
acts upstream of or within desmosome organization IMP
IMP: 通过突变表型推断
18703497 MGI
acts upstream of or within enamel mineralization IMP
IMP: 通过突变表型推断
18703497 MGI
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
acts upstream of or within iron ion transport IMP
IMP: 通过突变表型推断
18703497 MGI
acts upstream of or within lens morphogenesis in camera-type eye IMP
IMP: 通过突变表型推断
15728677 MGI
acts upstream of or within protein localization to cell junction IDA
IDA: 通过直接分析推断
22512338 MGI
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
15728677 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in adherens junction IDA
IDA: 通过直接分析推断
12515806 MGI
located in apical junction complex IDA
IDA: 通过直接分析推断
22512338 MGI
located in cell-cell contact zone IDA
IDA: 通过直接分析推断
23533177 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
11827984 MGI
is active in hippocampal mossy fiber to CA3 synapse IEP
IEP: 通过表达模式推断
11827984 MGI
is active in presynaptic active zone membrane IDA
IDA: 通过直接分析推断
11827984 MGI
is active in presynaptic active zone membrane IEP
IEP: 通过表达模式推断
11827984 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nectin-1

herpes virus entry mediator C

herpesvirus entry mediator C

nectin-1 alpha

nectin-1 delta

poliovirus receptor-related protein 1

重组 Nectin1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77468 Nectin-1 Protein, Mouse (HEK293, Fc) Q9JKF6 (Q31-A354) ≥95%
HY-P77469 Nectin-1 Protein, Mouse (HEK293, His) Q9JKF6 (Q31-A354) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09174 NECTIN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nectin1 NCBI NCBI:5818
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z