MPP4 - MAGUK p55 scaffold protein 4 Gene

中文名称：MAGUK p55 支架蛋白 4

种属: Homo sapiens

同用名: DLG6; ALS2CR5

关于 MPP4

功能概要

该基因编码膜相关鸟苷酸激酶 (MAGUK) 蛋白家族的一个成员，具有 N 末端 PDZ 结构域、中心 Src 同源 3 区域 (SH3) 和 C 末端鸟苷酸激酶样 (GUK) 结构域。该蛋白质定位于视网膜的外界膜，被认为在光感受器极性和特殊细胞间连接的组织中起作用。已经描述了选择性剪接的转录本变体，但尚未确定它们的生物学有效性。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family, with an N-terminal PDZ domain, a central Src homology 3 region (SH3), and a C-terminal guanylate kinase-like (GUK) domain. The protein is localized to the outer limiting membrane in the retina, and is thought to function in photoreceptor polarity and the organization of specialized intercellular junctions. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]