RPL36A - ribosomal protein L36a Gene

中文名称：核糖体蛋白 L36a

种属: Homo sapiens

同用名: L36A; L44L; MIG6; RPL44

关于 RPL36A

功能概要

细胞质核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白质与酵母核糖体蛋白 L44 具有序列相似性，属于核糖体蛋白 L44E (L36AE) 家族。尽管该基因被称为核糖体蛋白 L44 (RPL44) ，但其正式名称是核糖体蛋白 L36a (RPL36A) 。该基因与正式命名为类核糖体蛋白 L36a (RPL36AL) 的人类基因编码的蛋白质几乎相同；但是，它们是不同的基因。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。自然发生的通读转录发生在该基因座和异质核核糖核蛋白 H2 (H') 基因之间。[RefSeq 提供，2011 年 1 月]

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. Although this gene has been referred to as ribosomal protein L44 (RPL44), its official name is ribosomal protein L36a (RPL36A). This gene and the human gene officially named ribosomal protein L36a-like (RPL36AL) encode nearly identical proteins; however, they are distinct genes. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Naturally occurring read-through transcription occurs between this locus and the heterogeneous nuclear ribonucleoprotein H2 (H') gene. [provided by RefSeq, Jan 2011]