RPS20 - ribosomal protein S20 Gene

中文名称：核糖体蛋白 S20

种属: Homo sapiens

同用名: S20; uS10

基因 ID: 6224 | 基因类型: protein coding

关于 RPS20

Cytogenetic location: 8q12.1 Genomic coordinates (GRCh38): 8:56,067,254-56,074,506 (from NCBI)

This gene has 16 transcripts (splice variants), 190 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 727.4), fat (RPKM 436.0) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白 S10P 家族。它位于细胞质中。该基因与位于其第二个内含子中的小核仁 RNA 基因 U54 共同转录。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。已经为该基因鉴定了编码不同亚型的两个转录物变体。[RefSeq 提供，2009 年 4 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10P family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the small nucleolar RNA gene U54, which is located in its second intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Apr 2009]

RPS20 基因产物(2)

mRNA	Protein	Name
NM_001023.4	NP_001014.1	40S ribosomal protein S20 isoform 2
NM_001146227.3	NP_001139699.1	40S ribosomal protein S20 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables MDM2/MDM4 family protein binding	IPI IPI: 通过物理相互作用推断	23874713	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	18274552	GOA
enables structural constituent of ribosome	IDA IDA: 通过直接分析推断	23636399	GOA
enables ubiquitin ligase inhibitor activity	IDA IDA: 通过直接分析推断	23874713	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of signal transduction by p53 class mediator	IDA IDA: 通过直接分析推断	23874713	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytosolic ribosome	IDA IDA: 通过直接分析推断	23636399	GOA
part of cytosolic small ribosomal subunit	IDA IDA: 通过直接分析推断	8706699	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPS20 蛋白结构

Ribosomal_S10

0
100
119 a.a.

蛋白主名

其他名称

40S ribosomal protein S20

small ribosomal subunit protein uS10

RPS20 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属间	RPS20	P60866	ORF9b	Human SARS coronavirus	Q6S8E0	Y2H Pooling	22046132
种属间	RPS20	P60866	ORF9b	Human SARS coronavirus	Q6S8E0	Lumier	22046132
种属内	RPS20	P60866	LRRK2	Homo sapiens	Q5S007	Protein Array	24947832
种属内	RPS20	P60866	NEDD8	Homo sapiens	Q15843	Pull Down	18274552

种属间: 跨种属相互作用 种属内: 同种属相互作用

RPS20 抗体

目录号	产品名	应用	反应物种
HY-P83474	RPS20 Antibody (YA3219)	WB, IHC-P	Human, Mouse, Rat, Hamster

关联疾病

疾病名称

别名

Familial Colorectal Cancer Type X

Fcctx

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Diamond-Blackfan Anemia 1

Aase Syndrome	DBA1
Erythrogenesis Imperfecta	Aase-Smith Syndrome Ii
Dba	Blackfan-Diamond Syndrome
Bds	Anemia, Congenital Hypoplastic, Of Blackfan And Diamond
Anemia, Congenital Erythroid Hypoplastic	Red Cell Aplasia, Pure, Hereditary
Aregenerative Anemia, Chronic Congenital	Rps19-Related Diamond-Blackfan Anemia
Chronic Congenital Aregenerative Anemia	Congenital Erythroid Hypoplastic Anemia
Congenital Hypoplastic Anemia Of Blackfan And Diamond	Pure Hereditary Red Cell Aplasia
Anemia, Diamond-Blackfan, Type 1	Anemia, Diamond-Blackfan
Aase Smith Syndrome 2	Familial Hypoplastic Anaemia With Malformations
Constitutional Pure Red Cell Aplasia

Hereditary Mixed Polyposis Syndrome

Hmps

Shwachman-Diamond Syndrome 1

Shwachman-Diamond Syndrome	Shwachman Syndrome
Shwachman-Bodian-Diamond Syndrome	Sds
Pancreatic Insufficiency And Bone Marrow Dysfunction	Shwachman-Bodian Syndrome
SDS1	Lipomatosis Of Pancreas, Congenital
Congenital Lipomatosis Of Pancreas	Shwachman-Diamond Type Metaphyseal Dysplasia
Metaphyseal Chondrodysplasia, Shwachman Type	Shwachman-Diamond-Oski Syndrome

Lynch Syndrome

Hereditary Nonpolyposis Colon Cancer	Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Carcinoma	Hereditary Nonpolyposis Colorectal Neoplasms
Familial Nonpolyposis Colon Cancer	Hnpcc
Coca 1	Hereditary Defective Mismatch Repair Syndrome
Hereditary Non-Polyposis Colon Cancer	Hereditary Non-Polyposis Colon Cancer Syndrome
Hereditary Non-Polyposis Colorectal Cancer	Hereditary Non-Polyposis Colorectal Cancer Syndrome
Hereditary Nonpolyposis Colon Cancer Syndrome	Hereditary Nonpolyposis Colorectal Cancer Syndrome
Hereditary Nonpolyposis Colorectal Neoplasm	Hnpcc - Hereditary Nonpolyposis Colon Cancer
Cancer Family Syndrome	Familial Nonpolyposis Colorectal Cancer
Colon Cancer, Familial Nonpolyposis	Colorectal Neoplasms, Hereditary Nonpolyposis
Cancer, Colorectal, Nonpolyposis, Hereditary	Colorectal Cancer, Hereditary Nonpolyposis, Type 1

Dyskeratosis Congenita

Dyskeratosis Congenita Autosomal Dominant	Dc
Dkc	Zinsser-Engman-Cole Syndrome
Dyskeratosis Congenita, Autosomal Dominant	Autosomal Dominant Dyskeratosis Congenita
Dkca	Dyskeratosis Congenita Scoggins Type
Zinsser-Cole-Engman Syndrome	X-Linked Dyskeratosis Congenita
Hoyeraal-Hreidarsson Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12232	RPS20 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	RPS20	MGD	MGI:1914677
Rattus norvegicus	RPS20	RGD	RGD:621037
Bos taurus	RPS20	VGNC	VGNC:34133

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站点地图隐私声明

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上海工商

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沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RPS20 - ribosomal protein S20 Gene

关于 RPS20

功能概要

RPS20 基因产物(2)

RPS20 蛋白结构

RPS20 蛋白互作信息

RPS20 抗体

关联疾病

直系同源

热门区域

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RPS20 - ribosomal protein S20 Gene

关于 RPS20

功能概要

RPS20 基因产物(2)

RPS20 蛋白结构

RPS20 蛋白互作信息

RPS20 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z