2. Gene
  3. CLEC11A - C-type lectin domain containing 11A Gene

CLEC11A - C-type lectin domain containing 11A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 C 型凝集素结构域 11A

种属: Homo sapiens

同用名: P47; SCGF; LSLCL; CLECSF3

基因 ID: 6320 | 基因类型: protein coding

关于 CLEC11A

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:50,723,364-50,725,708 (from NCBI)

This gene has 2 transcripts (splice variants), 174 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 36.6), endometrium (RPKM 6.5) and 15 other tissues.

功能概要

该基因编码 C 型凝集素超家族的成员。编码的蛋白质是一种分泌的硫酸化糖蛋白，可作为原始造血祖细胞的生长因子。已经描述了另一种剪接变体，但尚未确定其生物学性质。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]

CLEC11A 基因产物(1)

mRNA Protein Name
NM_002975.3 NP_002966.1 C-type lectin domain family 11 member A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables growth factor activity IDA
IDA: 通过直接分析推断
11920266 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11920266 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
9442024 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CLEC11A 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (198 - 321)

  • 0
  • 100
  • 200
  • 300
  • 323 a.a.
蛋白主名 其他名称

C-type lectin domain family 11 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 3

CLEC11A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CLEC11A Q9Y240 NEFL Homo sapiens P07196
Y2H Array
32814053
种属内
CLEC11A Q9Y240 NEFL Homo sapiens P07196
Y2H Pooling
32814053
种属内
CLEC11A Q9Y240 NEFL Homo sapiens P07196
Validated Y2H
32814053
种属内
CLEC11A Q9Y240 TTR Homo sapiens P02766
Validated Y2H
32814053
种属内
CLEC11A Q9Y240 TTR Homo sapiens P02766
Y2H Array
32814053
种属内
CLEC11A Q9Y240 TTR Homo sapiens P02766
Y2H Pooling
32814053
种属内
CLEC11A Q9Y240 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属内
CLEC11A Q9Y240 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属内
CLEC11A Q9Y240 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
CLEC11A Q9Y240 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属内
CLEC11A Q9Y240 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Benign Mastocytoma
Chronic Granulomatous Disease

Cgd

Granulomatous Disease, Chronic

Autosomal Recessive Chronic Granulomatous Disease

X-Linked Chronic Granulomatous Disease

Bridges-Good Syndrome

Congenital Dysphagocytosis

Quie Syndrome

Chronic Septic Granulomatosis

Chronic Granulomatous Disorder

Granulomatous Disease Chronic

Granulomatous Disease, Chronic, X-Linked
Piebald Trait

Piebaldism

PBT

Partial Albinism

Albinoidism, Oculocutaneous, Autosomal Dominant
Esophageal Lipoma

Lipoma Of Esophagus
Solitary Mastocytoma Of The Skin

Cutaneous Solitary Mastocytoma

Skin Mastocytoma

Solitary Mastocytoma

Solitary Mastocytoma Of Skin

Mastocytoma, Skin
Aggressive Systemic Mastocytosis

Asm

Lymphadenopathic Mastocytosis With Eosinophilia
Osteopetrosis

Marble Bone Disease

Albers-Schonberg Disease

Osteopetroses

Marble Bones

Osteopetrosis And Related Disorders

Congenital Osteopetrosis

Marble Bone

Albers-Schoenberg Disease

Albers-Schonberg Osteopetrosis

Osteosclerosis Fragilis

Ivory Bones
Gastrointestinal Stromal Tumor

GIST

Gastrointestinal Stromal Tumors

Gastrointestinal Stromal Sarcoma

Gastrointestinal Stromal Tumor, Familial

Gant

Gastrointestinal Stromal Tumour

Stromal Tumor Of Gastrointestinal Tract

Stromal Tumour Of Gastrointestinal Tract

Gastrointestinal Stromal Neoplasm

Paraganglioma And Gastric Stromal Sarcoma

Plexosarcoma
Acute Promyelocytic Leukemia

Leukemia, Acute Promyelocytic

Acute Myeloblastic Leukemia Type 3

Aml M3

APL

Leukemia, Acute Promyelocytic, Somatic

Aml With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Apml

Acute Myeloblastic Leukemia 3

Acute Myeloid Leukemia With T(15

17)(Q22

Q12)

(Pml/Raralpha) And Variants

Acute Myeloblastic Leukaemia Type 3

Acute Myeloid Leukaemia M3

Acute Myeloid Leukemia M3

Acute Promyelocytic Leukaemia

M3 Anll

Myeloid Leukemia, Acute, M3

Leukemia Promyelocytic Acute

Leukemia, Promyelocytic, Acute

Leukemia, Acute, Promyelocytic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02780 CLEC11A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CLEC11A RGD RGD:3627
Mus musculus CLEC11A MGD MGI:1298219
Macaca mulatta CLEC11A VGNC VGNC:71167
Bos taurus CLEC11A VGNC VGNC:27422
Canis familiaris CLEC11A VGNC VGNC:49644
Others CLEC11A NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z