CCL15 - C-C motif chemokine ligand 15 Gene

中文名称：CC 基序趋化因子配体 15

种属: Homo sapiens

同用名: LKN1; NCC3; SY15; HCC-2; LKN-1; MIP-5; NCC-3; SCYL3; MIP-1D; MRP-2B; SCYA15; HMRP-2B; MIP-1 delta

关于 CCL15

功能概要

该基因位于 17 号染色体同一区域的一组相似基因中。这些基因编码 CC 细胞因子，它们是以两个相邻的半胱氨酸为特征的分泌蛋白。该基因的产物对 T 细胞和单核细胞具有趋化性，并通过 1 型 CC 趋化因子受体 (CCR1) 发挥作用。前蛋白被进一步加工成许多更小的功能性肽。自然发生的通读转录本从该基因进入下游基因 CCL14 (趋化因子 (CC 基序) 配体 14) 。[RefSeq 提供，2013 年 1 月]

This gene is located in a cluster of similar genes in the same region of chromosome 17. These genes encode CC cytokines, which are secreted proteins characterized by two adjacent cysteines. The product of this gene is chemotactic for T cells and monocytes, and acts through C-C Chemokine Receptor type 1 (CCR1). The proprotein is further processed into numerous smaller functional Peptides. Naturally-occurring readthrough transcripts occur from this gene into the downstream gene, CCL14 (chemokine (C-C motif) ligand 14). [provided by RefSeq, Jan 2013]