Casp7 - caspase 7 Gene

中文名称：半胱天冬酶 7

种属: Rattus norvegicus

关于 Casp7

功能概要

该基因编码的蛋白可启动半胱氨酸型肽酶活性。涉及多个过程，包括老化；白细胞凋亡过程；和横纹肌细胞分化。位于胞质溶胶和胞内膜界的细胞器中。多种疾病的生物标志物，包括子宫内膜炎；坐骨神经病;短暂性脑缺血； 2型糖尿病；和输尿管梗阻。该基因的人类直系同源物与阿尔茨海默病有关；乳腺癌;结肠癌;和肺非小细胞癌。与人 CASP7（caspase 7）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cysteine-type peptidase activity. Involved in several processes, including aging; leukocyte apoptotic process; and striated muscle cell differentiation. Located in cytosol and intracellular membrane-bounded organelle. Biomarker of several diseases, including endometritis; sciatic neuropathy; transient cerebral ischemia; type 2 diabetes mellitus; and ureteral obstruction. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (Caspase 7). [provided by Alliance of Genome Resources, Apr 2022]