2. Gene
  3. MMP27 - matrix metallopeptidase 27 Gene

MMP27 - matrix metallopeptidase 27 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：基质金属肽酶 27

种属: Homo sapiens

同用名: MMP-27

基因 ID: 64066 | 基因类型: protein coding

关于 MMP27

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,691,487-102,705,769 (from NCBI)

This gene has 1 transcript (splice variant), 441 orthologues and 23 paralogues. Low expression observed in reference dataset.

功能概要

基质金属蛋白酶 (MMP) 家族的蛋白质参与正常生理过程 (如胚胎发育、繁殖和组织重塑) 以及疾病过程 (如关节炎和转移) 中细胞外基质的分解。大多数 MMP's 被分泌为无活性的前蛋白，当被细胞外蛋白酶切割时被激活。[RefSeq 提供，2008 年 7 月]

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. [provided by RefSeq, Jul 2008]

MMP27 基因产物(1)

mRNA Protein Name
NM_022122.3 NP_071405.2 matrix metalloproteinase-27 precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
24548619 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MMP27 蛋白结构

PG_binding_1

PG_binding_1: Putative peptidoglycan binding domain (27 - 86)

Peptidase_M10

Peptidase_M10: Matrixin (106 - 261)

Hemopexin

Hemopexin: Hemopexin (285 - 326)

Hemopexin

Hemopexin: Hemopexin (330 - 370)

Hemopexin

Hemopexin: Hemopexin (376 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 513 a.a.
蛋白主名 其他名称

matrix metalloproteinase-27

matrix metalloprotease 27

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08546 MMP27 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta MMP27 VGNC VGNC:74749
Mus musculus MMP27 MGD MGI:3039232
Felis catus MMP27 VGNC VGNC:63538
Canis familiaris MMP27 VGNC VGNC:43286
Rattus norvegicus MMP27 RGD RGD:1306642
Bos taurus MMP27 VGNC VGNC:54886
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