SEMG2 - semenogelin 2 Gene

中文名称：semenogelin 2

种属: Homo sapiens

同用名: SGII

关于 SEMG2

功能概要

由该基因编码的分泌蛋白参与包裹射精精子的凝胶基质的形成。前列腺特异性抗原 (PSA) 的蛋白水解会分解凝胶基质，使精子能够更自由地移动。所编码的蛋白质的丰度低于类似的 semenogelin 蛋白质。已发现从该蛋白质中分离出的抗菌肽具有抗菌活性。编码这两种 semenogelin 蛋白的基因位于 20 号染色体上的一个簇中。[RefSeq 提供，2015 年 1 月]

The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An Antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015]