2. Gene
  3. MS4A6A - membrane spanning 4-domains A6A Gene

MS4A6A - membrane spanning 4-domains A6A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜 4 域 A6A

种属: Homo sapiens

同用名: CDA01; MS4A6; 4SPAN3; CD20L3; MST090; MSTP090; 4SPAN3.2

基因 ID: 64231 | 基因类型: protein coding

关于 MS4A6A

Cytogenetic location: 11q12.2 Genomic coordinates (GRCh38): 11:60,171,607-60,184,666 (from NCBI)

This gene has 21 transcripts (splice variants), 362 orthologues and 16 paralogues. Broad expression in lymph node (RPKM 27.7), spleen (RPKM 26.2) and 22 other tissues.

功能概要

该基因编码跨膜 4A 基因家族的成员。这个新生蛋白家族的成员具有共同的结构特征和相似的内含子/外显子剪接边界，并在造血细胞和非淋巴组织中表现出独特的表达模式。编码该蛋白质的基因定位于 11q12.1，位于一群家族成员中。该基因的可变剪接导致编码不同蛋白质亚型的几种转录变体。[RefSeq 提供，2011 年 10 月]

This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The gene encoding this protein is localized to 11q12.1, among a cluster of family members. Alternative splicing of this gene results in several transcript variants that encode different protein isoforms. [provided by RefSeq, Oct 2011]

MS4A6A 基因产物(5)

mRNA Protein Name
NM_001247999.2 NP_001234928.1 membrane-spanning 4-domains subfamily A member 6A isoform 4
NM_001330275.1 NP_001317204.1 membrane-spanning 4-domains subfamily A member 6A isoform 5
NM_022349.4 NP_071744.2 membrane-spanning 4-domains subfamily A member 6A isoform 2
NM_152851.2 NP_690590.1 membrane-spanning 4-domains subfamily A member 6A isoform 3
NM_152852.3 NP_690591.1 membrane-spanning 4-domains subfamily A member 6A isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in trans-Golgi network IDA
IDA: 通过直接分析推断
23874341 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MS4A6A 蛋白结构

CD20

CD20: CD20-like family (47 - 208)

  • 0
  • 100
  • 200
  • 248 a.a.
蛋白主名 其他名称

membrane-spanning 4-domains subfamily A member 6A

CD20 antigen-like 3

关联疾病

疾病名称 别名
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1

Nasu-Hakola Disease

Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy

Plosl

Nhd

Presenile Dementia With Bone Cysts

Plo-Sl

PLOSL1

Dementia, Prefrontal, With Bone Cysts

Dementia, Progressive, With Lipomembranous Polycystic Osteodysplasia

Brain-Bone-Fat Disease

Progressive Dementia With Lipomembranous Polycystic Osteodysplasia

Brain-Bone-Fat Disease
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08704 MS4A6A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MS4A6A RGD RGD:1305800
Macaca mulatta MS4A6A VGNC VGNC:101361
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z