CYP4F12 - cytochrome P450 family 4 subfamily F member 12 Gene

中文名称：细胞色素 P450 家族 4 亚家族 F 成员 12

种属: Homo sapiens

同用名: CYPIVF12; F22329_1

关于 CYP4F12

功能概要

该基因编码细胞色素 P450 酶超家族的成员。细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。这种蛋白质可能定位于内质网。当在酵母中表达时，该酶能够氧化花生四烯酸。它还可以催化 22:6n-3 和 22:5n-3 多不饱和长链脂肪酸的环氧化反应。该基因是 19 号染色体上细胞色素 P450 基因簇的一部分。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 4 月]

This gene encodes a member of the Cytochrome P450 superfamily of Enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the Enzyme is capable of oxdizing arachidonic acid. It can also catalyze the epoxidation of 22:6n-3 and 22:5n-3 polyunsaturated long-chain fatty acids. This gene is part of a cluster of Cytochrome P450 genes on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]