1. Gene
  2. NPY2R - neuropeptide Y receptor Y2 Gene

NPY2R - neuropeptide Y receptor Y2 Gene

中文名称:神经肽 Y 受体 Y2

种属: Rattus norvegicus

基因 ID: 66024 | 基因类型: protein coding

关于 NPY2R

Biased expression in Brain (RPKM 13.6), Uterus (RPKM 2.4) and 1 other tissue.

功能概要

该基因编码的蛋白可启动肽 YY 受体活性。参与多个过程,包括细胞通讯的负调节;调节神经系统过程;和分泌调节。位于质膜。是质膜的组成部分。用于研究儿童失神癫痫和精神抑郁症。肥胖的生物标志物。该基因的人类直系同源物与亨廷顿病有关;病态肥胖;和肥胖。与人 NPY2R(神经肽 Y 受体 Y2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables peptide YY receptor activity. Involved in several processes, including negative regulation of cell communication; regulation of nervous system process; and regulation of secretion. Located in plasma membrane. Is integral component of plasma membrane. Used to study childhood absence epilepsy and mental depression. Biomarker of obesity. Human ortholog(s) of this gene implicated in Huntington's disease; morbid obesity; and obesity. Orthologous to human NPY2R (Neuropeptide Y Receptor Y2). [provided by Alliance of Genome Resources, Apr 2022]

NPY2R 基因产物(1)

mRNA Protein Name
NM_023968.1 NP_076458.1 neuropeptide Y receptor type 2

NPY2R 蛋白结构

7tmA_NPY2R

7tmA_NPY2R: cd15399 (50 - 335)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (51 - 77)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (84 - 109)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (122 - 152)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (163 - 184)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (215 - 244)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (260 - 290)

7tmA_NPY2R

7tmA_NPY2R: cd15399 (303 - 328)

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  • 381 a.a.
蛋白主名 其他名称

neuropeptide Y receptor type 2

neuropeptide Y-Y2 receptor

neuropeptide Y/peptide YY-Y2 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens NPY2R NCBI NCBI:4887