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  2. Rgs8 - regulator of G-protein signaling 8 Gene

Rgs8 - regulator of G-protein signaling 8 Gene

中文名称:G 蛋白信号调节器 8

种属: Mus musculus

同用名: 6530413N01Rik

基因 ID: 67792 | 基因类型: protein coding

关于 Rgs8

Chromosome 1: 153,528,771-153,576,069 forward strand.GRCm39:CM000994.3

This gene has 10 transcripts (splice variants), 199 orthologues and 23 paralogues. Biased expression in cerebellum adult (RPKM 84.), cortex adult (RPKM 9.6) and 4 other tissues.

功能概要

预计该基因编码的蛋白可启动 G 蛋白 α 亚基结合活性和 GTP 酶激活剂活性。预计参与G蛋白偶联的乙酰胆碱受体信号通路; GTP酶活性的正调节;和多巴胺受体信号通路的调控。预测作用于 G 蛋白偶联受体信号通路的上游或内部。预测位于树突中;神经细胞体膜;和核。预测为质膜细胞质侧的外在成分。在中枢神经系统和视网膜中表达。与人类 RGS8(G 蛋白信号转导 8 的调节因子)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G-protein alpha-subunit binding activity and GTPase activator activity. Predicted to be involved in G protein-coupled acetylcholine receptor signaling pathway; positive regulation of GTPase activity; and regulation of Dopamine Receptor signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in dendrite; neuronal cell body membrane; and nucleus. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in central nervous system and retina. Orthologous to human RGS8 (regulator of G protein signaling 8). [provided by Alliance of Genome Resources, Apr 2022]

Rgs8 基因产物(3)

mRNA Protein Name
NM_026380.3 NP_080656.2 regulator of G-protein signaling 8 isoform 1
NM_001347115.1 NP_001334044.1 regulator of G-protein signaling 8 isoform 2
NM_001357525.1 NP_001344454.1 regulator of G-protein signaling 8 isoform 1

Rgs8 蛋白结构

RGS_RGS8

RGS_RGS8: cd08711 (45 - 169)

  • 0
  • 100
  • 180 a.a.
蛋白主名 其他名称

regulator of G-protein signaling 8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rgs8 NCBI NCBI:85397