2. Gene
  3. KLF9 - KLF transcription factor 9 Gene

KLF9 - KLF transcription factor 9 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：KLF 转录因子 9

种属: Homo sapiens

同用名: BTEB; BTEB1

基因 ID: 687 | 基因类型: protein coding

关于 KLF9

Cytogenetic location: 9q21.12 Genomic coordinates (GRCh38): 9:70,384,604-70,414,657 (from NCBI)

This gene has 1 transcript (splice variant), 196 orthologues and 22 paralogues. Ubiquitous expression in fat (RPKM 44.7), gall bladder (RPKM 34.1) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种转录因子，可与位于启动子中的 GC 盒元件结合。编码的蛋白质与单个 GC 盒的结合会抑制 mRNA 表达，而与串联重复的 GC 盒元件结合会激活转录。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a transcription factor that binds to GC box elements located in the promoter. Binding of the encoded protein to a single GC box inhibits mRNA expression while binding to tandemly repeated GC box elements activates transcription. [provided by RefSeq, Jul 2008]

KLF9 基因产物(1)

mRNA Protein Name
NM_001206.4 NP_001197.1 Krueppel-like factor 9
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to cortisol stimulus IDA
IDA: 通过直接分析推断
22711835 GOA
involved in circadian rhythm IEP
IEP: 通过表达模式推断
22711835 GOA
involved in negative regulation of keratinocyte proliferation IMP
IMP: 通过突变表型推断
22711835 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
22711835 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KLF9 蛋白结构

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (159 - 186)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (190 - 212)

  • 0
  • 100
  • 200
  • 244 a.a.
蛋白主名 其他名称

Krueppel-like factor 9

BTE-binding protein 1

关联疾病

疾病名称 别名
Otosclerosis

Otospongiosis
Endometrial Cancer

Endometrial Carcinoma

Endometrial Neoplasm

Malignant Neoplasm Of Endometrium

Endometrioid Carcinoma

Endometrial Neoplasms

Carcinoma, Endometrioid

Endometrial Cancer, Familial

Endometrial Carcinoma, Somatic

Endometrial Cancer, Susceptibility To

Endometrial Ca

Malignant Endometrial Neoplasm

Neoplasm Of Endometrium

Primary Malignant Neoplasm Of Endometrium

Tumor Of Endometrium

Carcinoma Of The Endometrium

Endometrioid Carcinoma Of Female Reproductive System

ENDMC

Carcinoma Endometrioid

Endometrial Cancers

Cancer, Endometrial

Uterine Corpus Cancer
Familial Thyroid Dyshormonogenesis

Thyroid Dyshormonogenesis

Familial Dyshormonogenetic Goiter
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07346 KLF9 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus KLF9 RGD RGD:70934
Felis catus KLF9 VGNC VGNC:102943
Canis familiaris KLF9 VGNC VGNC:53731
Mus musculus KLF9 MGD MGI:1333856
Bos taurus KLF9 VGNC VGNC:30632
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