2. Gene
  3. TCEA3 - transcription elongation factor A3 Gene

TCEA3 - transcription elongation factor A3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转录延伸因子 A3

种属: Homo sapiens

同用名: TFIIS; TFIIS.H

基因 ID: 6920 | 基因类型: protein coding

关于 TCEA3

Cytogenetic location: 1p36.12 Genomic coordinates (GRCh38): 1:23,380,909-23,424,748 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 221 orthologues and 3 paralogues. Ubiquitous expression in colon (RPKM 19.3), ovary (RPKM 18.5) and 23 other tissues.

功能概要

预测启用 DNA 结合活性和锌离子结合活性。预计参与转录、DNA 模板化和转录、DNA 模板化的调节。预测位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated and transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TCEA3 基因产物(1)

mRNA Protein Name
NM_003196.3 NP_003187.1 transcription elongation factor A protein 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TCEA3 蛋白结构

Med26

Med26: TFIIS helical bundle-like domain (28 - 80)

TFIIS_M

TFIIS_M: Transcription factor S-II (TFIIS), central domain (183 - 297)

TFIIS_C

TFIIS_C: Transcription factor S-II (TFIIS) (308 - 346)

  • 0
  • 100
  • 200
  • 300
  • 348 a.a.
蛋白主名 其他名称

transcription elongation factor A protein 3

rhabdomyosarcoma antigen MU-RMS-40.22

TCEA3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TCEA3 O75764 LEO1 Homo sapiens Q8WVC0
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spastic Paraplegia 24, Autosomal Recessive

SPG24

Spastic Paraplegia 24

Hereditary Spastic Paraplegia 24

Autosomal Recessive Spastic Paraplegia Type 24

Autosomal Recessive Spastic Paraplegia 24
Cockayne Syndrome

Cockayne'S Syndrome

Dwarfism-Retinal Atrophy-Deafness Syndrome

Neill-Dingwall Syndrome

Progeria-Like Syndrome

Progeroid Nanism

Cs
Endocervical Adenocarcinoma

Endocervical Carcinoma
Rhabdomyosarcoma
De Sanctis-Cacchione Syndrome

Xerodermic Idiocy

Xeroderma Pigmentosum With Neurologic Manifestation

DSC

Xerodermic Idiocy Of De Sanctis And Cacchione
Uv-Sensitive Syndrome

Uvss

Uv Sensitive Syndrome

Ultraviolet Sensitive Syndrome
Cockayne Syndrome B

Cockayne Syndrome Type 2

Cockayne Syndrome, Type B

Cockayne Syndrome Type Ii

CSB

Cockayne Syndrome 2

Cockayne Syndrome Type B

Ckn2

Cockayne Syndrome, Type Ii
Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum

XPV

Xeroderma Pigmentosum Variant Type

Xeroderma Pigmentosum With Normal Dna Repair Rates

Photosensitivity With Defective Dna Synthesis

Xp

De Sanctis-Cacchione Syndrome

Desanctis-Cacchione Syndrome

Xeroderma Pigmentosa

Xerodermic Idiocy

Xeroderma Pigmentosum Variant

Xp - [Xeroderma Pigmentosum]

Atrophoderma Pigmentosum
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14293 TCEA3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta TCEA3 VGNC VGNC:78281
Mus musculus TCEA3 MGD MGI:1196908
Rattus norvegicus TCEA3 RGD RGD:1311369
Canis familiaris TCEA3 VGNC VGNC:47184
Bos taurus TCEA3 VGNC VGNC:35681
Felis catus TCEA3 VGNC VGNC:66016
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