TEC - tec protein tyrosine kinase Gene

中文名称：tec 蛋白酪氨酸激酶

种属: Homo sapiens

同用名: PSCTK4

关于 TEC

功能概要

由该基因编码的蛋白质属于包含 pleckstrin 同源结构域的非受体蛋白-酪氨酸激酶的 Tec 家族。 Tec 家族激酶参与细胞因子受体、淋巴细胞表面抗原、异源三聚体 G 蛋白偶联受体和整合素分子的细胞内信号传导机制。它们也是调节免疫功能的关键参与者。 Tec 激酶是 T 细胞信号传导的组成部分，在 T 细胞活化中具有独特的作用。该基因可能与骨髓增生异常综合征有关。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of Cytokine Receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and Integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]