2. Gene
  3. GPR137B - G protein-coupled receptor 137B Gene

GPR137B - G protein-coupled receptor 137B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 137B

种属: Homo sapiens

同用名: TM7SF1

基因 ID: 7107 | 基因类型: protein coding

关于 GPR137B

Cytogenetic location: 1q42.3 Genomic coordinates (GRCh38): 1:236,142,539-236,208,907 (from NCBI)

This gene has 5 transcripts (splice variants), 259 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 12.9), brain (RPKM 8.4) and 23 other tissues.

功能概要

参与多个过程，包括 TORC1 信号的正调控；蛋白质定位到溶酶体的正向调节；和 GTPase 活性的调节。位于溶酶体膜。 [由基因组资源联盟提供，2022 年 4 月]

Involved in several processes, including positive regulation of TORC1 signaling; positive regulation of protein localization to lysosome; and regulation of GTPase activity. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR137B 基因产物(1)

mRNA Protein Name
NM_003272.4 NP_003263.1 integral membrane protein GPR137B
蛋白主名 其他名称

integral membrane protein GPR137B

transmembrane 7 superfamily member 1 (upregulated in kidney)

GPR137B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
GPR137B O60478 TRIM32 Homo sapiens Q13049
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa 60

RP60

Retinitis Pigmentosa, Type 60
Ceroid Lipofuscinosis, Neuronal, 1

Neuronal Ceroid Lipofuscinosis 1

CLN1

Infantile Neuronal Ceroid Lipofuscinosis

Cln1 Disease

Santavuori-Haltia Disease

Ceroid Lipofuscinosis, Neuronal, 1, Variable Age At Onset

Neuronal Ceroid Lipofuscinosis 1 Variable Age Of Onset

Ceroid Lipofuscinosis Neuronal 1

Cln1 Variable Age At Onset

Infantile Batten Disease

Neuronal Ceroid Lipofuscinosis, Infantile

Hagberg-Santavuori Disease

Incl

Juvenile Neuronal Ceroid Lipofuscinosis With Granular Osmiophilic Deposits

Neuronal Ceroid Lipofuscinosis With Variable Age At Onset

Santavuori Disease

Lipofuscinosis, Ceroid, Neuronal, Type 1

Ceroid Lipofuscinosis, Neuronal 1, Infantile
Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib

IGHD1B

Ighd Ib

Growth Hormone Deficiency, Isolated, Type Ib

Congenital Ighd Type Ib

Congenital Isolated Gh Deficiency Type Ib

Congenital Isolated Growth Hormone Deficiency Type Ib

Dwarfism Of Sindh

Pituitary Dwarfism I

Isolated Growth Hormone Deficiency Type 1b

Ighd 1b

Growth Hormone Deficiency, Isolated, 1b
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05659 GPR137B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GPR137B MGD MGI:1891463
Macaca mulatta GPR137B VGNC VGNC:72930
Felis catus GPR137B VGNC VGNC:62673
Bos taurus GPR137B VGNC VGNC:29551
Rattus norvegicus GPR137B RGD RGD:1307342
Canis familiaris GPR137B VGNC VGNC:41398
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