2. Gene
  3. CLEC3B - C-type lectin domain family 3 member B Gene

CLEC3B - C-type lectin domain family 3 member B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：C 型凝集素结构域家族 3 成员 B

种属: Homo sapiens

同用名: TN; TNA; MCDR4

基因 ID: 7123 | 基因类型: protein coding

关于 CLEC3B

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:45,026,303-45,036,071 (from NCBI)

This gene has 3 transcripts (splice variants), 251 orthologues and 2 paralogues. Broad expression in spleen (RPKM 63.9), fat (RPKM 63.1) and 20 other tissues.

功能概要

启用钙离子结合活性；肝素结合活性；和 kringle 域绑定活动。参与骨矿化和细胞对转化生长因子 β 刺激的反应。位于细胞质中；细胞外空间；和颗粒状成分。含有胶原蛋白的细胞外基质的一部分。与骨关节炎有关。 [由基因组资源联盟提供，2022 年 4 月]

Enables calcium ion binding activity; heparin binding activity; and kringle domain binding activity. Involved in bone mineralization and cellular response to transforming growth factor beta stimulus. Located in cytoplasm; extracellular space; and granular component. Part of collagen-containing extracellular matrix. Implicated in osteoarthritis. [provided by Alliance of Genome Resources, Apr 2022]

CLEC3B 基因产物(2)

mRNA Protein Name
NM_001308394.2 NP_001295323.1 tetranectin isoform 2
NM_003278.3 NP_003269.2 tetranectin isoform 1precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
9786936 GOA
enables heparin binding IDA
IDA: 通过直接分析推断
10727405 GOA
enables kringle domain binding IPI
IPI: 通过物理相互作用推断
9786936 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bone mineralization IDA
IDA: 通过直接分析推断
7798325 GOA
involved in ossification IEP
IEP: 通过表达模式推断
7798325 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
7798325 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
7798325 GOA
located in granular component IDA
IDA: 通过直接分析推断
15848710 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CLEC3B 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (88 - 198)

  • 0
  • 100
  • 202 a.a.
蛋白主名 其他名称

tetranectin

plasminogen kringle 4-binding protein

重组 CLEC3B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7815 Tetranectin/CLEC3B Protein, Human (181a.a, HEK293, His) AAH11024.1 (E22-V202) ≥95%

CLEC3B 抗体

目录号 产品名 应用 反应物种
HY-P82150 Tetranectin Antibody (YA1895) WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

关联疾病

疾病名称 别名
Macular Dystrophy, Retinal, 4

MCDR4
Ureteric Orifice Cancer

Malignant Neoplasm Of Ureteric Orifice Of Urinary Bladder

Malignant Tumor Of Ureteric Orifice

Orifice Of The Ureter
Osteoarthritis

Osteoarthrosis

Degenerative Joint Disease

Hypertrophic Arthritis

Arthropathy

Degenerative Polyarthritis

Degenerative Arthritis

Osteoarthrosis And Allied Disorder

Arthritis, Degenerative

Oa

Osteoarthritis Deformans

Osteoarthrosis Deformans

Kashin-Beck Disease
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
Pelvic Inflammatory Disease

Pid
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02790 CLEC3B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CLEC3B VGNC VGNC:54591
Macaca mulatta CLEC3B VGNC VGNC:110373
Bos taurus CLEC3B VGNC VGNC:27429
Felis catus CLEC3B VGNC VGNC:60950
Rattus norvegicus CLEC3B RGD RGD:1311031
Mus musculus CLEC3B MGD MGI:104540
Others CLEC3B NCBI
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