TNFAIP2 - TNF alpha induced protein 2 Gene

中文名称：肿瘤坏死因子α诱导蛋白 2

种属: Homo sapiens

同用名: B94; EXOC3L3

关于 TNFAIP2

功能概要

该基因被鉴定为其表达可被脐静脉内皮细胞中的肿瘤坏死因子α (TNF) 诱导的基因。该基因的表达被证明在表达视黄酸受体 α 融合蛋白的致癌版本的细胞系中由视黄酸诱导，这表明该基因可能是急性早幼粒细胞白血病中的视黄酸靶基因。[RefSeq 提供，2008 年 7 月]

This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia. [provided by RefSeq, Jul 2008]