1. Gene
  2. VIPR2 - vasoactive intestinal peptide receptor 2 Gene

VIPR2 - vasoactive intestinal peptide receptor 2 Gene

中文名称:血管活性肠肽受体 2

种属: Homo sapiens

同用名: VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3

基因 ID: 7434 | 基因类型: protein coding

关于 VIPR2

Cytogenetic location: 7q36.3 Genomic coordinates (GRCh38): 7:159,028,175-159,144,867 (from NCBI)

This gene has 4 transcripts (splice variants), 259 orthologues and 42 paralogues. Broad expression in ovary (RPKM 1.9), brain (RPKM 1.9) and 20 other tissues.

功能概要

该基因编码血管活性肠肽 (一种小的神经肽) 的受体。血管活性肠肽参与平滑肌松弛、外分泌和内分泌以及肺和肠上皮细胞中的水和离子流动。它的作用是通过与激活腺苷酸环化酶的鸟嘌呤核苷酸结合蛋白相关的整合膜受体来实现的。[RefSeq 提供,2011 年 8 月]

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates Adenylate Cyclase. [provided by RefSeq, Aug 2011]

VIPR2 基因产物(3)

mRNA Protein Name
NM_001304522.2 NP_001291451.1 vasoactive intestinal polypeptide receptor 2 isoform 2 precursor
NM_001308259.1 NP_001295188.1 vasoactive intestinal polypeptide receptor 2 isoform 3
NM_003382.5 NP_003373.2 vasoactive intestinal polypeptide receptor 2 isoform 1 precursor

VIPR2 蛋白结构

HRM

HRM: Hormone receptor domain (50 - 111)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (125 - 371)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 438 a.a.
蛋白主名 其他名称

vasoactive intestinal polypeptide receptor 2

PACAP type III receptor

重组 VIPR2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76128 VIPR2 Protein, Human (HEK293, Fc) P41587 (E24-V126) ≥95%

关联疾病

疾病名称 别名
Schizophrenia 16

SCZD16

Schizophrenia Susceptibility Locus, Chromosome 7q36.3-Related

Chromosome 7q36.3 Duplication Syndrome, 362-Kb

Gastric Leiomyoma

Leiomyoma Of The Stomach

Central Serous Chorioretinopathy

Central Serous Chorioretinopathy After Bone Marrow Transplantation

Central Serous Choroidopathy

Cscr

Central Serous Retinopathy

Central Serous Choroidoretinopathy

Holoprosencephaly

Holoprosencephaly Sequence

Hpe

Hpe - [Holoprosencephaly]

Myopia

Near-Sightedness

Short-Sightedness

Nearsightedness

Nearsighted

Near Vision

Close Sighted

Myopic

Short-Sighted

Near Sighted

Sudden Infant Death Syndrome

SIDS

Sudden Infant Death Syndrome, Susceptibility To

Cot Death

Crib Death

Sudden Death Of Nonspecific Cause In Infancy

Sudden Infant Death

Death, Sudden, Syndrome, Infant

Advanced Sleep Phase Syndrome

Fasps

Familial Advanced Sleep-Phase Syndrome

Advanced Sleep Phase Syndrome, Familial

Familial Advanced Sleep Phase Syndrome

Sleep Phase Syndrome, Advanced, Familial

Advanced Sleep-Phase Syndrome, Familial

Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib

IGHD1B

Ighd Ib

Growth Hormone Deficiency, Isolated, Type Ib

Congenital Ighd Type Ib

Congenital Isolated Gh Deficiency Type Ib

Congenital Isolated Growth Hormone Deficiency Type Ib

Dwarfism Of Sindh

Pituitary Dwarfism I

Isolated Growth Hormone Deficiency Type 1b

Ighd 1b

Growth Hormone Deficiency, Isolated, 1b

Major Depressive Disorder

Seasonal Affective Disorder

Unipolar Depression

Depression

MDD

Depressive Disorder

Unipolar Depression, Susceptibility To

Major Depressive Disorder 1

Major Depressive Disorder, Response To Citalopram Therapy In

Major Depressive Disorder 2

Winter Depression

Single Major Depressive Episode

Sad

Clinical Depression

Major Depression

Depressive Syndrome

Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment

Seasonal Affective Disorder, Susceptibility To

Recurrent Major Depression

Affective Disorder, Seasonal

Depression In A Seasonal Pattern

Depression

Seasonal

Major Depressive Disorder With A Seasonal Pattern

Seasonal Depression

Seasonal Mood Disorder

Mental Depression

Recurrent Major Depressive Episodes

Intellectual Developmental Disorder, X-Linked, Syndromic, Wilson-Turner Type

Wilson-Turner Syndrome

WTS

Mrxs6

X-Linked Intellectual Disability-Gynecomastia-Obesity Syndrome

Mrxswt

Wilson-Turner X-Linked Mental Retardation Syndrome

Mental Retardation, X-Linked, Syndromic 6

Mental Retardation, X-Linked, With Gynecomastia And Obesity

Intellectual Disability, X-Linked, Syndromic 6

Intellectual Disability, X-Linked, With Gynecomastia And Obesity

Wilson Turner Intellectual Disability Syndrome

X-Linked Intellectual Disability - Gynecomastia - Obesity

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Migraine With Or Without Aura 1

Migraine

Migraine With Or Without Aura, Susceptibility To, 1

Migraine Disorder

Migraine Variant

Migraines

Migraine Disorders

Mgr1

Mgau

Ma

Migraine With Or Without Aura

Classic Migraine

Common Migraine

Disorder, Migraine

Headache Migraine

Headache Migrainous

Migraine Headache

Migraine Syndrome

Headache Including Migraine

Migraine, Susceptibility To

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris VIPR2 VGNC VGNC:48266
Bos taurus VIPR2 VGNC VGNC:36800
Mus musculus VIPR2 MGD MGI:107166
Rattus norvegicus VIPR2 RGD RGD:3962
Felis catus VIPR2 VGNC VGNC:66946
Macaca mulatta VIPR2 VGNC VGNC:78772
Others VIPR2 NCBI