VIPR2 蛋白, Human (HEK293, Fc)

VIPR2 protein, serving as a receptor for Vasoactive Intestinal Peptide (VIP) and Pituitary Adenylate Cyclase-Activating Peptide (PACAP-38 and -27), activates adenylyl cyclase and can also couple with phospholipase C. Its versatile signaling pathways emphasize its pivotal role in transducing signals from VIP and PACAP, participating in cellular processes regulated by cyclic AMP and phosphoinositide signaling cascades. VIPR2 Protein, Human (HEK293, Fc) is the recombinant human-derived VIPR2 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of VIPR2 Protein, Human (HEK293, Fc) is 103 a.a., with molecular weight of 45-60 kDa.

VIPR2 蛋白充当血管活性肠肽 (VIP) 以及垂体腺苷酸环化酶激活肽（PACAP-38 和 -27）的受体。该受体的活性由 G 蛋白介导，导致腺苷酸环化酶激活。此外，VIPR2 具有与磷脂酶 C 偶联的能力，展示了其在信号传导途径中的多功能性。这些相互作用凸显了 VIPR2 在转导 VIP 和 PACAP 信号中的关键作用，从而参与由环 AMP 和磷酸肌醇信号级联调节的细胞过程。

Human

HEK293

C-mFc

P41587 (E24-V126)

7434  [NCBI]

ECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILV

45-60 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.