WNT2B - Wnt family member 2B Gene

中文名称：Wnt 家族成员 2B

种属: Homo sapiens

同用名: WNT13

基因 ID: 7482 | 基因类型: protein coding

关于 WNT2B

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,466,541-112,530,165 (from NCBI)

This gene has 4 transcripts (splice variants), 200 orthologues, 18 paralogues and is associated with 1 phenotype. Broad expression in ovary (RPKM 4.3), skin (RPKM 3.1) and 21 other tissues.

功能概要

该基因编码高度保守的分泌信号因子的无翼型 MMTV 整合位点 (Wnt) 家族的成员。 Wnt 家族成员在各种发育过程中发挥作用，包括调节细胞生长和分化，并以 Wnt 核心结构域为特征。该基因可能在人类发育和致癌作用中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 5 月]

This gene encodes a member of the wingless-type MMTV integration site (Wnt) family of highly conserved, secreted signaling factors. Wnt family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

WNT2B 基因产物(3)

mRNA	Protein	Name
NM_001291880.1	NP_001278809.1	protein Wnt-2b isoform 3
NM_004185.4	NP_004176.2	protein Wnt-2b isoform WNT-2B1
NM_024494.3	NP_078613.1	protein Wnt-2b isoform WNT-2B2

基因本体论

生物过程

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in canonical Wnt signaling pathway	IDA IDA: 通过直接分析推断	11741304	GOA
involved in canonical Wnt signaling pathway	IMP IMP: 通过突变表型推断	15135146	GOA
involved in chondrocyte differentiation	IEP IEP: 通过表达模式推断	15135146	GOA
involved in forebrain regionalization	IEP IEP: 通过表达模式推断	15164427	GOA
involved in hematopoietic stem cell proliferation	IDA IDA: 通过直接分析推断	9787155	GOA
involved in male gonad development	IEP IEP: 通过表达模式推断	17848411	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

WNT2B 蛋白结构

wnt

0
100
200
300
391 a.a.

蛋白主名

其他名称

protein Wnt-2b

XWNT2, Xenopus, homolog of

WNT2B 抗体

目录号	产品名	应用	反应物种
HY-P82679	Wnt2b Antibody (YA2424)	WB, ICC/IF	Human, Mouse, Rat

关联疾病

疾病名称

别名

Diarrhea 9

DIAR9

Diarrhea, Type 9

Diarrhea

Diarrhoea

Diarrhea Of Presumed Infectious Origin

Osmotic Diarrhea

Gastric Cancer

Stomach Cancer	Gastric Carcinoma
Stomach Carcinoma	Gastric Cancer, Somatic
Gastric Neoplasm	Carcinoma Of Stomach
Stomach Neoplasms	Malignant Neoplasm Of Stomach
Gastric Cancer Risk After H. Pylori Infection	Cancer Of The Stomach
Adult Stomach Cancer	Adult Stomach Carcinoma
GASC	Gastric Cancer Intestinal
Gastric Cancers	Gastric Carcinomas
Cancer, Gastric	Stomach Neoplasm
Malignant Neoplasm Of Body Of Stomach	Malignant Tumor Of Lesser Curve Of Stomach
Gastrocarcinoma Of Unspecified Site	Leather Bottle Stomach
Carcinoma Of Fundus Of Stomach	Cancer Of Fundus Of Stomach
Primary Malignant Neoplasm Of Body Of Stomach	Cancer Of Body Of Stomach
Primary Malignant Neoplasm Of Pyloric Antrum	Pyloric Antrum Cancer
Malignant Tumour Of Stomach

Neural Tube Defects

Spina Bifida	Neural Tube Defect
NTD	Neural Tube Defects, Susceptibility To
Spinal Dysraphism	Spina Bifida, Susceptibility To
Rachischisis	Cleft Spine
Open Spine	Hydrocele Spinalis
Neural Tube Defect Nos	Sb - [Spina Bifida]
Spinal Hernia Nos	Spinal Fissure Nos

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Exudative Vitreoretinopathy

Familial Exudative Vitreoretinopathy	Fevr
Criswick-Schepens Syndrome	Exudative Vitreoretinopathy, Familial
Vitreoretinopathy, Exudative )	Exudative Vitreoretinopathy 1

Norrie Disease

Atrophia Bulborum Hereditaria	Episkopi Blindness
Pseudoglioma	ND
Norrie-Warburg Disease	Anderson-Warburg Syndrome
Fetal Iritis Syndrome	Norrie Syndrome
Norrie-Warburg Syndrome	Ndp
Congenital Progressive Oculo-Acoustico-Cerebral Degeneration	Norrie'S Disease
Oligophrenia Microphthalmus	Pseudoglioma Congenita
Whitnall-Norman Syndrome

Robinow Syndrome

Acral Dysostosis With Facial And Genital Abnormalities	Fetal Face Syndrome
Robinow Dwarfism	Mesomelic Dwarfism-Small Genitalia Syndrome
Robinow-Silverman-Smith Syndrome	Costovertebral Segmentation Defect With Mesomelia
Covesdem Syndrome	Robinow'S Syndrome
Robinow-Silverman Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15833	WNT2B Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	WNT2B	VGNC	VGNC:36958
Macaca mulatta	WNT2B	VGNC	VGNC:78797
Rattus norvegicus	WNT2B	RGD	RGD:69346
Felis catus	WNT2B	VGNC	VGNC:80403
Mus musculus	WNT2B	MGD	MGI:1261834
Canis familiaris	WNT2B	VGNC	VGNC:48423

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

WNT2B - Wnt family member 2B Gene

关于 WNT2B

功能概要

WNT2B 基因产物(3)

WNT2B 蛋白结构

WNT2B 抗体

关联疾病

直系同源

热门区域

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WNT2B - Wnt family member 2B Gene

关于 WNT2B

功能概要

WNT2B 基因产物(3)

WNT2B 蛋白结构

WNT2B 抗体

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z