2. Gene
  3. Arpc2 - actin related protein 2/3 complex, subunit 2 Gene

Arpc2 - actin related protein 2/3 complex, subunit 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：肌动蛋白相关蛋白 2/3 复合物，亚基2

种属: Mus musculus

同用名: 34kDa; p34-Arc; 2210023N03Rik

基因 ID: 76709 | 基因类型: protein coding

关于 Arpc2

Chromosome 1: 74,275,243-74,307,368 forward strand.GRCm39:CM000994.3

This gene has 4 transcripts (splice variants), 240 orthologues and is associated with 13 phenotypes. Ubiquitous expression in placenta adult (RPKM 131.5), bladder adult (RPKM 118.3) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATPase 绑定活动；肌动蛋白丝结合活性；和谷氨酸受体结合活性。预计是细胞骨架的结构成分。在肌动蛋白丝聚合的正调节和底物粘附依赖性细胞扩散的正调节的上游或内部起作用。位于多个细胞成分中，包括粘着斑；谷氨酸能突触；和肌细胞投射膜。以镜头坑表示。与人类 ARPC2（肌动蛋白相关蛋白 2/3 复合亚基 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATPase binding activity; actin filament binding activity; and glutamate receptor binding activity. Predicted to be a structural constituent of Cytoskeleton. Acts upstream of or within positive regulation of actin filament polymerization and positive regulation of substrate adhesion-dependent cell spreading. Located in several cellular components, including focal adhesion; glutamatergic synapse; and muscle cell projection membrane. Is expressed in lens pit. Orthologous to human ARPC2 (actin related protein 2/3 complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Arpc2 基因产物(2)

mRNA Protein Name
NM_029711.2 NP_083987.1 actin-related protein 2月3日 complex subunit 2
NM_001357387.1 NP_001344316.1 actin-related protein 2月3日 complex subunit 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18836449 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of actin filament polymerization IDA
IDA: 通过直接分析推断
18836449 MGI
acts upstream of or within positive regulation of substrate adhesion-dependent cell spreading IMP
IMP: 通过突变表型推断
22689987 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell leading edge IDA
IDA: 通过直接分析推断
18836449 MGI
located in endosome IDA
IDA: 通过直接分析推断
22689987 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
12473693 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
24413018 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24413018 MGI
located in muscle cell projection membrane IDA
IDA: 通过直接分析推断
22553210 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
22689987 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
34269176 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
34269176 MGI
is active in synapse EXP
EXP: 通过实验结果推断
24413018 MGI
is active in synapse IDA
IDA: 通过直接分析推断
24413018 MGI
is active in synaptic vesicle membrane IDA
IDA: 通过直接分析推断
34269176 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Arpc2 蛋白结构

P34-Arc

P34-Arc: pfam04045 (56 - 283)

  • 0
  • 100
  • 200
  • 300 a.a.
蛋白主名 其他名称

actin-related protein 2/3 complex subunit 2

arp2/3 complex 34 kDa subunit

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-114657A Benproperine phosphate Inhibitor 99.35% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01015 ARPC2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01016 Arpc2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS01017 Arpc2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arpc2 NCBI NCBI:10109
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