2. Gene
  3. ZNF207 - zinc finger protein 207 Gene

ZNF207 - zinc finger protein 207 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 207

种属: Homo sapiens

同用名: BuGZ; hBuGZ

基因 ID: 7756 | 基因类型: protein coding

关于 ZNF207

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:32,350,157-32,381,885 (from NCBI)

This gene has 17 transcripts (splice variants) and 251 orthologues. Ubiquitous expression in bone marrow (RPKM 30.2), lymph node (RPKM 22.5) and 25 other tissues.

功能概要

启用微管结合活动。参与多个过程，包括有丝分裂核分裂；有丝分裂纺锤体组装检查点信号；和蛋白质稳定。位于着丝粒；核腔;和主轴矩阵。 [由基因组资源联盟提供，2022 年 4 月]

Enables microtubule binding activity. Involved in several processes, including mitotic nuclear division; mitotic spindle assembly checkpoint signaling; and protein stabilization. Located in kinetochore; nuclear lumen; and spindle matrix. [provided by Alliance of Genome Resources, Apr 2022]

ZNF207 基因产物(3)

mRNA Protein Name
NM_001032293.3 NP_001027464.1 BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform b
NM_001098507.2 NP_001091977.1 BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform c
NM_003457.4 NP_003448.1 BUB3-interacting and GLEBS motif-containing protein ZNF207 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microtubule binding IDA
IDA: 通过直接分析推断
24462186 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
21988832 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in attachment of spindle microtubules to kinetochore IMP
IMP: 通过突变表型推断
24462186 GOA
involved in mitotic sister chromatid segregation IMP
IMP: 通过突变表型推断
24462186 GOA
involved in mitotic spindle assembly IDA
IDA: 通过直接分析推断
26388440 GOA
involved in mitotic spindle assembly checkpoint signaling IMP
IMP: 通过突变表型推断
24462186 GOA
involved in protein stabilization IMP
IMP: 通过突变表型推断
24462186 GOA
involved in regulation of chromosome segregation IMP
IMP: 通过突变表型推断
24462186 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in kinetochore IDA
IDA: 通过直接分析推断
24462187 GOA
located in kinetochore IMP
IMP: 通过突变表型推断
24462186 GOA
located in nucleus IDA
IDA: 通过直接分析推断
24462186 GOA
located in spindle matrix IDA
IDA: 通过直接分析推断
26388440 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

BUB3-interacting and GLEBS motif-containing protein ZNF207

ZNF207 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ZNF207 O43670 BUB3 Homo sapiens O43684
Y2H
22365833
Intra ZNF207 O43670 BUB3 Homo sapiens O43684
Confocal
21988832
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Chromosome 15q26-Qter Deletion Syndrome

Drayer Syndrome

15q26 Deletion Syndrome

Distal 15q Deletion Syndrome

Distal Monosomy 15q

Telomeric 15q Deletion Syndrome

Monosomy 15q26
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-161303 ZNF207-IN-1 98.03% 否
HY-RS16109 ZNF207 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF207 RGD RGD:1308121
Felis catus ZNF207 VGNC VGNC:67275
Mus musculus ZNF207 MGD MGI:1340045
Macaca mulatta ZNF207 VGNC VGNC:78870
Bos taurus ZNF207 VGNC VGNC:37225
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