2. Gene
  3. CSDE1 - cold shock domain containing E1 Gene

CSDE1 - cold shock domain containing E1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 E1 的冷休克结构域

种属: Homo sapiens

同用名: UNR; D1S155E

基因 ID: 7812 | 基因类型: protein coding

关于 CSDE1

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:114,716,916-114,757,984 (from NCBI)

This gene has 53 transcripts (splice variants), 240 orthologues and is associated with 1 phenotype. Ubiquitous expression in fat (RPKM 208.0), thyroid (RPKM 164.2) and 25 other tissues.

功能概要

启用 RNA 茎环结合活性。参与 IRES 依赖性病毒翻译启动；核转录的 mRNA 分解代谢过程，不衰变；和应力颗粒组装。位于高尔基体；胞质溶胶；和质膜。 CRD 介导的 mRNA 稳定性复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex. [provided by Alliance of Genome Resources, Apr 2022]

CSDE1 基因产物(6)

mRNA Protein Name
NM_001007553.3 NP_001007554.1 cold shock domain-containing protein E1 isoform 1
NM_001130523.3 NP_001123995.1 cold shock domain-containing protein E1 isoform 3
NM_001242891.2 NP_001229820.1 cold shock domain-containing protein E1 isoform 4
NM_001242892.2 NP_001229821.1 cold shock domain-containing protein E1 isoform 1
NM_001242893.2 NP_001229822.1 cold shock domain-containing protein E1 isoform 2
NM_007158.6 NP_009089.4 cold shock domain-containing protein E1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RISC complex binding IDA
IDA: 通过直接分析推断
32161113 GOA
enables RNA stem-loop binding IDA
IDA: 通过直接分析推断
17947529 GOA
enables lncRNA binding IPI
IPI: 通过物理相互作用推断
36354136 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CRD-mediated mRNA stabilization IDA
IDA: 通过直接分析推断
11051545 GOA
involved in IRES-dependent viral translational initiation IDA
IDA: 通过直接分析推断
17947529 GOA
involved in negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
IDA: 通过直接分析推断
11051545 GOA
involved in nuclear-transcribed mRNA catabolic process, no-go decay IMP
IMP: 通过突变表型推断
15314026 GOA
involved in positive regulation of cytoplasmic translation IDA
IDA: 通过直接分析推断
11051545 GOA
involved in positive regulation of translation IMP
IMP: 通过突变表型推断
36354136 GOA
involved in stress granule assembly IMP
IMP: 通过突变表型推断
29395067 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CRD-mediated mRNA stability complex IDA
IDA: 通过直接分析推断
15314026 GOA
located in cytosol IDA
IDA: 通过直接分析推断
11051545 GOA
part of mCRD-mediated mRNA stability complex IPI
IPI: 通过物理相互作用推断
11051545 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CSDE1 蛋白结构

CSD

CSD: 'Cold-shock' DNA-binding domain (73 - 135)

CSD

CSD: 'Cold-shock' DNA-binding domain (232 - 293)

CSD

CSD: 'Cold-shock' DNA-binding domain (397 - 457)

CSD

CSD: 'Cold-shock' DNA-binding domain (567 - 627)

CSD

CSD: 'Cold-shock' DNA-binding domain (721 - 783)

SUZ-C

SUZ-C: SUZ-C motif (802 - 835)

  • 0
  • 200
  • 400
  • 600
  • 844 a.a.
蛋白主名 其他名称

cold shock domain-containing protein E1

N-ras upstream gene protein

CSDE1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CSDE1 O75534 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
种属内
CSDE1 O75534 HID1 Homo sapiens Q8IV36
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

CSDE1 抗体

目录号 产品名 应用 反应物种
HY-P83083 CSDE1 Antibody (YA2828) WB, IHC-F, IHC-P, ICC/IF, IP Human

关联疾病

疾病名称 别名
Bulbar Polio

Poliomyelitis, Bulbar

Bulbar Poliomyelitis
Persistent Generalized Lymphadenopathy

Pgl

Persistant Generalized Lymphadenopathy
Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03225 CSDE1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris CSDE1 VGNC VGNC:39650
Macaca mulatta CSDE1 VGNC VGNC:71605
Felis catus CSDE1 VGNC VGNC:61213
Mus musculus CSDE1 MGD MGI:92356
Rattus norvegicus CSDE1 RGD RGD:619726
Bos taurus CSDE1 VGNC VGNC:27751
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