2. Gene
  3. Lpar4 - lysophosphatidic acid receptor 4 Gene

Lpar4 - lysophosphatidic acid receptor 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶血磷脂酸受体 4

种属: Mus musculus

同用名: LPA4; p2y9; Gpr23; 5730485F04Rik

基因 ID: 78134 | 基因类型: protein coding

关于 Lpar4

Chromosome X: 105,964,231-105,977,506 forward strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 174 orthologues, 16 paralogues and is associated with 22 phenotypes. Biased expression in limb E14.5 (RPKM 7.9), CNS E11.5 (RPKM 2.4) and 1 other tissues.

功能概要

该基因编码的蛋白可启动溶血磷脂酸结合活性和溶血磷脂酸受体活性。预计参与磷脂酶 C 激活 G 蛋白偶联信号通路中 Rho 蛋白信号转导的正向调节和胞质钙离子浓度的正向调节。预测作用于信号转导的上游或内部。位于质膜。以多种结构表达，包括鳃弓；未来的大脑；肢;鼻子;和骨架。与人类 LPAR4（溶血磷脂酸受体 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables lysophosphatidic acid binding activity and lysophosphatidic acid receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to act upstream of or within signal transduction. Located in plasma membrane. Is expressed in several structures, including branchial arch; future brain; limb; nose; and skeleton. Orthologous to human LPAR4 (lysophosphatidic acid receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Lpar4 基因产物(1)

mRNA Protein Name
NM_175271.4 NP_780480.2 lysophosphatidic acid receptor 4
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lysophosphatidic acid binding IDA
IDA: 通过直接分析推断
17166850 MGI
enables lysophosphatidic acid receptor activity IDA
IDA: 通过直接分析推断
17166850 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
17166850 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Lpar4 蛋白结构

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 66)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 321)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (73 - 98)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (110 - 140)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (152 - 174)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (200 - 229)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (241 - 271)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (289 - 314)

  • 0
  • 100
  • 200
  • 300
  • 370 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 4

G protein-coupled receptor 23

LPA receptor 4

LPA-4

P2Y purinoceptor 9

purinergic receptor 9

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07755 LPAR4 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07756 Lpar4 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07757 Lpar4 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpar4 NCBI NCBI:2846
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